CDC7 protein, human

Known as: HsCDC7, CDC7 Cell Division Cycle 7-Like 1 (S. cerevisiae), huCDC7 
Cell division cycle 7-related protein kinase (574 aa, ~64 kDa) is encoded by the human CDC7 gene. This protein plays a role in protein… (More)
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
Cdc7 is an essential kinase that promotes DNA replication by activating origins of replication. Here, we characterized the potent… (More)
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2007
2007
Cdc7 kinase promotes and regulates DNA replication in eukaryotic organisms. Multiple mechanisms modulating kinase activity in… (More)
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Highly Cited
2005
Highly Cited
2005
Sphingosine kinase (SK) 1 catalyzes the formation of the bioactive lipid sphingosine 1-phosphate, and has been implicated in… (More)
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Review
2002
Review
2002
DNA replication results from the action of a staged set of highly regulated processes. Among the stages of DNA replication… (More)
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Highly Cited
2002
Highly Cited
2002
Sphingosine-1-phosphate (S1P) is a highly bioactive sphingolipid involved in diverse biological processes leading to changes in… (More)
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Highly Cited
1999
Highly Cited
1999
The Cdc7-Dbf4 kinase is essential for regulating initiation of DNA replication in Saccharomyces cerevisiae. Previously, we… (More)
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Highly Cited
1998
Highly Cited
1998
The Cdc7p protein kinase plays an essential, but undefined, role promoting S phase in the budding yeast, Saccharomyces cerevisiae… (More)
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Highly Cited
1998
Highly Cited
1998
The long-standing conclusion that the Cdc7 kinase of Saccharomyces cerevisiae is required only to trigger S phase has been… (More)
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Highly Cited
1997
Highly Cited
1997
Saccharomyces cerevisiae Cdc7 kinase is essential for initiation of DNA replication, and Hsk1, a related kinase of… (More)
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Highly Cited
1993
Highly Cited
1993
Yeast Cdc7 protein kinase and Dbf4 protein are both required for the initiation of DNA replication at the G1/S phase boundary of… (More)
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