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CDC7 protein, human

Known as: HsCDC7, CDC7 Cell Division Cycle 7-Like 1 (S. cerevisiae), huCDC7 
Cell division cycle 7-related protein kinase (574 aa, ~64 kDa) is encoded by the human CDC7 gene. This protein plays a role in protein… 
National Institutes of Health

Related topics

Related topics

26 relations
CDC7 geneCDC7 wt AlleleCDK2 protein, humanCDK3 protein, human

Broader (2)

Cell Cycle ProteinsProtein-Serine-Threonine Kinases

Narrower (1)

Leucine-Rich Repeat Serine/Threonine-Protein Kinase 2

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
3D Pharmacophore Model-Assisted Discovery of Novel CDC7 Inhibitors.
A ligand-based 3D pharmacophore model for serine/threonine kinase CDC7 inhibition was created and successfully applied in the… 
2010
2010
Hsk1 kinase and Cdc45 regulate replication stress-induced checkpoint responses in fission yeast
In fission yeast, replication fork arrest activates the replication checkpoint effector kinase Cds1Chk2/Rad53 through the Rad3ATR… 
2006
2006
Identification of Functional Domains within the Septation Initiation Network Kinase, Cdc7*
The septation initiation network (SIN) serves to coordinate cytokinesis with mitotic exit in the fission yeast… 
Highly Cited
2003
Highly Cited
2003
Interaction and assembly of murine pre-replicative complex proteins in yeast and mouse cells.
2003
2003
The antidepressant fluoxetine blocks the human small conductance calcium-activated potassium channels SK1, SK2 and SK3
Review
1999
Review
1999
CDC7 kinase complex as a molecular switch for DNA replication.
Cdc7 kinase and its activator Dbf4 protein, originally identified in budding yeast Saccharomyces cerevisiae, are widely conserved… 
1999
1999
DNA replication in vertebrates requires a homolog of the Cdc7 protein kinase.
CDC7 is an essential gene required for DNA replication in Saccharomyces cerevisiae. Cdc7p homologs have recently been identified… 
1997
1997
Analyses of Saccharomyces cerevisiae Cdc7 kinase point mutants: dominant-negative inhibition of DNA replication on overexpression of kinase-negative Cdc7 proteins
Saccharomyces cerevisiae Cdc7 kinase is required for initiation of S phase, and its kinase activity, which is positively… 
1993
1993
Yeast pre-meiotic DNA replication utilizes mitotic origin ARS1 independently of CDC7 function
In budding yeast, mitotic DNA replication initiates at sequence-specific replication origins, the prototype for which is ARS1… 
1988
1988
Characterisation of the CDC7 gene product of Saccharomyces cerevisiae as a protein kinase needed for the initiation of mitotic DNA synthesis.
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