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Leu-Enkephalin

Known as: Tyr-Gly-Gly-Phe-Leu, YGGPL 
Leu-enkephalin (5 aa, ~1 kDa) is encoded by the human PENK gene. This protein is involved in the activation of mu and delta opioid receptors.
National Institutes of Health

Related topics

Related topics

6 relations

Broader (1)

Enkephalin, Leucine
Extracellular SpaceG Protein-Coupled Receptor SignalingNociceptionPENK gene

Papers overview

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2011
2011
Oxidative and nitrative modifications of enkephalins by human neutrophils: effect of nitroenkephalin on leukocyte functional responses
Neutrophils play a major role in acute inflammation by generating reactive oxygen/nitrogen species. Opioid peptides, including… 
1998
1998
Characterization of immunoreactive dynorphin B and β-endorphin in human plasma
1997
1997
Differential effects of beta-endorphin and Met- and Leu-enkephalin on steroid hormone-induced lordosis in ovariectomized female rats.
The effect of intrathirdventricular (I.T.V.) injections of beta-endorphin, anti-beta-endorphin antiserum, Met-enkephalin, Leu… 
1997
1997
Tumour-derived, endocrine, exogenous and therapeutic factors differentially modulate cytokine secretion in whole blood cell culture.
1994
1994
Expression of opioid peptides in cells and stroma of human breast cancer and adenofibromas.
1992
1992
Reciprocal effects between opioid peptides and human polymorphonuclear leukocytes--I. Chemical modifications of Leu-enkephalin by phorbol myristate acetate-stimulated polymorphonuclear leukocytes.
1991
1991
Effect of opiate receptor agonists on myocardial energy metabolism in rats with hemorrhagic shock
A disturbance of myocardial energy metabolism is one cause of the hemodynamic disorders associated with shock, including… 
1986
1986
RIA/chromatographic evidence for novel opioid peptide(s) in Squilla…
1986
1986
Specific binding of Leu-enkephalin to small and large intestinal epithelial cells from guinea-pig.
1984
1984
Leu-enkephalin binding to cultured human T lymphocytes.
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