Skip to search formSkip to main contentSkip to account menu

LY-49 receptor

Known as: Killer Cell Lectin-Like Receptor, Subfamily A, Member 1, Ly49 Antigen, KLRA1 
An inhibitory subclass of NK cell lectin-like receptors that interacts with CLASS I MAJOR HISTOCOMPATIBILITY ANTIGENS and prevents the activation of… 
National Institutes of Health

Related topics

Related topics

21 relations
Homo sapiensImmune Cell Activation ProcessIn BloodKLRA1 wt Allele

Narrower (6)

Klra1 protein, mouseKlra5 protein, mouseLy49s3 protein, ratNK Cell Lectin-Like Receptor Subfamily A, Member 1

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2002
Highly Cited
2002
A BAC contig map of the Ly49 gene cluster in 129 mice reveals extensive differences in gene content relative to C57BL/6 mice.
The murine Ly49 gene family is functionally analogous to the human killer cell Ig-like receptor (KIR) family of class I major… 
Review
2001
Review
2001
Intracellular Signaling by the Killer Immunoglobulin-Like Receptors and Ly49
Once thought to be promiscuous killers, it is now known that natural killer (NK) cells possess an elaborate array of receptors… 
Highly Cited
2001
Highly Cited
2001
Acquisition of External Major Histocompatibility Complex Class I Molecules by Natural Killer Cells Expressing Inhibitory Ly49 Receptors
Murine natural killer (NK) cells express inhibitory Ly49 receptors specific for major histocompatibility complex (MHC) class I… 
Highly Cited
2001
Highly Cited
2001
Expression of Ly49E and CD94/NKG2 on Fetal and Adult NK Cells1
Murine NK cells express inhibitory receptors belonging to the Ly49 and CD94/NKG2 family. Ly49E and CD94 are the only NK cell… 
Highly Cited
1999
Highly Cited
1999
Cutting edge: expression of functional CD94/NKG2A inhibitory receptors on fetal NK1.1+Ly-49- cells: a possible mechanism of tolerance during NK cell development.
Fetal liver- and thymus-derived NK1.1+ cells do not express known Ly-49 receptors. Despite the absence of Ly-49 inhibitory… 
Highly Cited
1999
Highly Cited
1999
Induction of DAP12 phosphorylation, calcium mobilization, and cytokine secretion by Ly49H
The ability of several Ly49 family members to inhibit natural killer (NK) cell functions through recruitment of SHP‐1 phosphatase… 
Highly Cited
1997
Highly Cited
1997
Type I transmembrane receptor with inhibitory function in mouse mast cells and NK cells.
Review
1997
Review
1997
Inhibitory receptors abound?
Receptor biologists have traditionally focused on receptors that are physiologically coupled to inductive responses such as gene… 
Highly Cited
1991
Highly Cited
1991
Ly-49 multigene family. New members of a superfamily of type II membrane proteins with lectin-like domains.
Ly-49 (YE1/48, A1) is a dimer protein expressed on subpopulations of murine NK cells. It is a member of a superfamily of type II… 
Highly Cited
1981
Highly Cited
1981
Detection of ABH tissue isoantigens by immunoperoxidase methods in normal and neoplastic urothelium. Comparison with the erythrocyte adherence method.
The expression of the ABH blood group antigens (BGAg) by carcinomas of the urinary bladder at the time of initial biopsy heralds… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)