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LY-49 receptor
Known as:
Killer Cell Lectin-Like Receptor, Subfamily A, Member 1
, Ly49 Antigen
, KLRA1
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An inhibitory subclass of NK cell lectin-like receptors that interacts with CLASS I MAJOR HISTOCOMPATIBILITY ANTIGENS and prevents the activation of…
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National Institutes of Health
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Related topics
Related topics
21 relations
Homo sapiens
Immune Cell Activation Process
In Blood
KLRA1 wt Allele
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Narrower (6)
Klra1 protein, mouse
Klra5 protein, mouse
Ly49s3 protein, rat
NK Cell Lectin-Like Receptor Subfamily A, Member 1
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2002
Highly Cited
2002
A BAC contig map of the Ly49 gene cluster in 129 mice reveals extensive differences in gene content relative to C57BL/6 mice.
A. Makrigiannis
,
Amanda T Pau
,
P. Schwartzberg
,
D. McVicar
,
T. Beck
,
S. Anderson
Genomics
2002
Corpus ID: 35456973
The murine Ly49 gene family is functionally analogous to the human killer cell Ig-like receptor (KIR) family of class I major…
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Review
2001
Review
2001
Intracellular Signaling by the Killer Immunoglobulin-Like Receptors and Ly49
D. McVicar
,
D. Burshtyn
Science's STKE
2001
Corpus ID: 23176189
Once thought to be promiscuous killers, it is now known that natural killer (NK) cells possess an elaborate array of receptors…
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Highly Cited
2001
Highly Cited
2001
Acquisition of External Major Histocompatibility Complex Class I Molecules by Natural Killer Cells Expressing Inhibitory Ly49 Receptors
A. Sjöström
,
M. Eriksson
,
+4 authors
P. Höglund
Journal of Experimental Medicine
2001
Corpus ID: 14431725
Murine natural killer (NK) cells express inhibitory Ly49 receptors specific for major histocompatibility complex (MHC) class I…
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Highly Cited
2001
Highly Cited
2001
Expression of Ly49E and CD94/NKG2 on Fetal and Adult NK Cells1
K. van Beneden
,
F. Stevenaert
,
+4 authors
G. Leclercq
Journal of Immunology
2001
Corpus ID: 3122865
Murine NK cells express inhibitory receptors belonging to the Ly49 and CD94/NKG2 family. Ly49E and CD94 are the only NK cell…
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Highly Cited
1999
Highly Cited
1999
Cutting edge: expression of functional CD94/NKG2A inhibitory receptors on fetal NK1.1+Ly-49- cells: a possible mechanism of tolerance during NK cell development.
P. Sivakumar
,
Anasuya Gunturi
,
+9 authors
Vinay Kumar
Journal of Immunology
1999
Corpus ID: 7800212
Fetal liver- and thymus-derived NK1.1+ cells do not express known Ly-49 receptors. Despite the absence of Ly-49 inhibitory…
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Highly Cited
1999
Highly Cited
1999
Induction of DAP12 phosphorylation, calcium mobilization, and cytokine secretion by Ly49H
P. Gosselin
,
L. Mason
,
J. Willette-Brown
,
J. Ortaldo
,
D. McVicar
,
S. Anderson
Journal of Leukocyte Biology
1999
Corpus ID: 6330210
The ability of several Ly49 family members to inhibit natural killer (NK) cell functions through recruitment of SHP‐1 phosphatase…
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Highly Cited
1997
Highly Cited
1997
Type I transmembrane receptor with inhibitory function in mouse mast cells and NK cells.
S. Rojo
,
D. Burshtyn
,
Eric O Long
,
N. Wagtmann
Journal of Immunology
1997
Corpus ID: 28348486
Review
1997
Review
1997
Inhibitory receptors abound?
J. Cambier
Proceedings of the National Academy of Sciences…
1997
Corpus ID: 22522802
Receptor biologists have traditionally focused on receptors that are physiologically coupled to inductive responses such as gene…
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Highly Cited
1991
Highly Cited
1991
Ly-49 multigene family. New members of a superfamily of type II membrane proteins with lectin-like domains.
S. Wong
,
J. Freeman
,
Colm A. Kelleher
,
D. Mager
,
Fumio Takei
Journal of Immunology
1991
Corpus ID: 21546231
Ly-49 (YE1/48, A1) is a dimer protein expressed on subpopulations of murine NK cells. It is a member of a superfamily of type II…
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Highly Cited
1981
Highly Cited
1981
Detection of ABH tissue isoantigens by immunoperoxidase methods in normal and neoplastic urothelium. Comparison with the erythrocyte adherence method.
J. Coon
,
R. Weinstein
American Journal of Clinical Pathology
1981
Corpus ID: 13642742
The expression of the ABH blood group antigens (BGAg) by carcinomas of the urinary bladder at the time of initial biopsy heralds…
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