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LMP2A-Specific Cytotoxic T-Lymphocytes

Known as: LMP2A-CTL, EBV-Specific Cytotoxic T-Lymphocytes, LMP2A CTL 
A preparation of cytotoxic T-lymphocytes (CTL), specifically reactive to Epstein-Barr virus (EBV) latent membrane protein-2A (LMP2A), with potential… Expand
National Institutes of Health

Related topics

Related topics

3 relations
Autologous Epstein-Barr Virus-Specific Cytotoxic T LymphocytesNCIt Antineoplastic Agent Terminologyautologous Epstein-Barr virus-specific cytotoxic T lymphocytes (cell)

Papers overview

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Highly Cited
2007
Highly Cited
2007
CTL Fail to Accumulate at Sites of HIV-1 Replication in Lymphoid Tissue12
The inability of HIV-1-specific CTL to fully suppress virus replication as well as the failure of administration of exogenous CTL… Expand
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Highly Cited
2005
Highly Cited
2005
High frequency of antitumor T cells in the blood of melanoma patients before and after vaccination with tumor antigens
After vaccination of melanoma patients with MAGE antigens, we observed that even in the few patients showing tumor regression… Expand
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Review
2004
Review
2004
Tumor antigen-specific T helper cells in cancer immunity and immunotherapy
Historically, cancer-directed immune-based therapies have focused on eliciting a cytotoxic T cell (CTL) response, primarily due… Expand
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Highly Cited
1999
Highly Cited
1999
The memory cytotoxic T-lymphocyte (CTL) response to human cytomegalovirus infection contains individual peptide-specific CTL clones that have undergone extensive expansion in vivo.
Human cytomegalovirus (HCMV)-specific CD8(+) cytotoxic T lymphocytes (CTL) appear to play an important role in the control of… Expand
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Highly Cited
1998
Highly Cited
1998
Identification of cytotoxic T cell epitopes within Epstein-Barr virus (EBV) oncogene latent membrane protein 1 (LMP1): evidence for HLA A2 supertype-restricted immune recognition of EBV-infected…
Epstein-Barr virus (EBV) nuclear antigen 1 (EBNA1) and latent membrane proteins (LMP) are the only antigens consistently… Expand
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Highly Cited
1997
Highly Cited
1997
Enhancement of cellular immunity in melanoma patients immunized with a peptide from MART-1/Melan A.
PURPOSE In this study, we tested the effectiveness of a melanoma-associated antigen-derived peptide, MART-1(27-35), in eliciting… Expand
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Highly Cited
1997
Highly Cited
1997
Cytotoxic T lymphocytes specific for a nonpolymorphic proteinase 3 peptide preferentially inhibit chronic myeloid leukemia colony-forming units.
We previously showed that a peptide (PR1) derived from the primary granule enzyme proteinase 3 induced peptide specific cytotoxic… Expand
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Highly Cited
1995
Highly Cited
1995
Recognition of multiple epitopes in the human melanoma antigen gp100 by tumor-infiltrating T lymphocytes associated with in vivo tumor regression.
Four of ten HLA-A2-restricted melanoma specific CTL that were derived from tumor-infiltrating lymphocytes (TIL) and administered… Expand
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Highly Cited
1994
Highly Cited
1994
Virus-specific CD8+ cytotoxic T-lymphocyte activity associated with control of viremia in primary human immunodeficiency virus type 1 infection.
Human immunodeficiency virus type 1 (HIV-1) Env-, Gag-, Pol-, Nef-, and Tat-specific cytotoxic T-lymphocyte (CTL) activities were… Expand
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Highly Cited
1980
Highly Cited
1980
Dendritic cells are accessory cells for the development of anti- trinitrophenyl cytotoxic T lymphocytes
This study establishes that dendritic cells (DC) are the critical accessory cells for the development of anti-trinitrophenol (TNP… Expand
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