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LMP2A-Specific Cytotoxic T-Lymphocytes

Known as: LMP2A-CTL, EBV-Specific Cytotoxic T-Lymphocytes, LMP2A CTL 
A preparation of cytotoxic T-lymphocytes (CTL), specifically reactive to Epstein-Barr virus (EBV) latent membrane protein-2A (LMP2A), with potential… Expand
National Institutes of Health

Related topics

Related topics

3 relations
Autologous Epstein-Barr Virus-Specific Cytotoxic T LymphocytesNCIt Antineoplastic Agent Terminologyautologous Epstein-Barr virus-specific cytotoxic T lymphocytes (cell)

Papers overview

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Highly Cited
2005
Highly Cited
2005
High frequency of antitumor T cells in the blood of melanoma patients before and after vaccination with tumor antigens
After vaccination of melanoma patients with MAGE antigens, we observed that even in the few patients showing tumor regression… Expand
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Review
2004
Review
2004
Tumor antigen-specific T helper cells in cancer immunity and immunotherapy
Historically, cancer-directed immune-based therapies have focused on eliciting a cytotoxic T cell (CTL) response, primarily due… Expand
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Highly Cited
1999
Highly Cited
1999
The Memory Cytotoxic T-Lymphocyte (CTL) Response to Human Cytomegalovirus Infection Contains Individual Peptide-Specific CTL Clones That Have Undergone Extensive Expansion In Vivo
ABSTRACT Human cytomegalovirus (HCMV)-specific CD8+ cytotoxic T lymphocytes (CTL) appear to play an important role in the control… Expand
Highly Cited
1997
Highly Cited
1997
Enhancement of cellular immunity in melanoma patients immunized with a peptide from MART-1/Melan A.
PURPOSE In this study, we tested the effectiveness of a melanoma-associated antigen-derived peptide, MART-1(27-35), in eliciting… Expand
Highly Cited
1997
Highly Cited
1997
Cytotoxic T lymphocytes specific for a nonpolymorphic proteinase 3 peptide preferentially inhibit chronic myeloid leukemia colony-forming units.
We previously showed that a peptide (PR1) derived from the primary granule enzyme proteinase 3 induced peptide specific cytotoxic… Expand
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Highly Cited
1995
Highly Cited
1995
Recognition of multiple epitopes in the human melanoma antigen gp100 by tumor-infiltrating T lymphocytes associated with in vivo tumor regression.
Four of ten HLA-A2-restricted melanoma specific CTL that were derived from tumor-infiltrating lymphocytes (TIL) and administered… Expand
Highly Cited
1994
Highly Cited
1994
Virus-specific CD8+ cytotoxic T-lymphocyte activity associated with control of viremia in primary human immunodeficiency virus type 1 infection
Human immunodeficiency virus type 1 (HIV-1) Env-, Gag-, Pol-, Nef-, and Tat-specific cytotoxic T-lymphocyte (CTL) activities were… Expand
Highly Cited
1994
Highly Cited
1994
Human immunodeficiency virus (HIV) nef-specific cytotoxic T lymphocytes in noninfected heterosexual contact of HIV-infected patients.
We report on the detection of HIV-specific cytotoxic T lymphocytes (CTL) among 23 regular partners of HIV-infected individuals… Expand
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Highly Cited
1988
Highly Cited
1988
Human cytomegalovirus-specific cytotoxic T cells. Relative frequency of stage-specific CTL recognizing the 72-kD immediate early protein and glycoprotein B expressed by recombinant vaccinia viruses
CTL are held to be an important host defense mechanism in persistent herpes-virus infections. We have therefore studied the… Expand
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Highly Cited
1980
Highly Cited
1980
Dendritic cells are accessory cells for the development of anti- trinitrophenyl cytotoxic T lymphocytes
This study establishes that dendritic cells (DC) are the critical accessory cells for the development of anti-trinitrophenol (TNP… Expand
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