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LGI1 protein, human

Known as: Leucine-Rich Glioma-Inactivated Protein 1, leucine-rich, glioma-inactivated 1 protein, human, BA512J3.1 
Predominantly expressed in neural tissues and encoded by human LGI1 Gene, a 557-amino acid 64-kD precursor yields mature 60-kD putative tumor… 
National Institutes of Health

Related topics

Related topics

7 relations
Congenital EpilepsyHomo sapiensInhibition of Cancer Cell GrowthLGI1 gene

Broader (1)

Proteins

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2017
Review
2017
The LGI1–ADAM22 protein complex in synaptic transmission and synaptic disorders
Highly Cited
2011
Highly Cited
2011
VGKC antibodies in pediatric encephalitis presenting with status epilepticus
Background: Voltage-gated potassium channel antibodies (VGKC Ab) are associated with limbic encephalitis and neuromyotonia in… 
Review
2011
Review
2011
Immune‐mediated steroid‐responsive epileptic spasms and epileptic encephalopathy associated with VGKC‐complex antibodies
Autoantibodies that bind to voltage‐gated potassium‐channel complex proteins (VGKC‐complex antibodies) occur frequently in adults… 
2010
2010
Mutations in LGI1 gene in Japanese families with autosomal dominant lateral temporal lobe epilepsy: The first report from Asian families
Autosomal dominant lateral temporal lobe epilepsy (ADLTE) caused by LGI1 (leucine‐rich gene, glioma‐inactivated‐1) mutations is a… 
2007
2007
STRUCTURAL ANOMALY OF LEFT LATERAL TEMPORAL LOBE IN EPILEPSY DUE TO MUTATED LGI1
Autosomal dominant lateral temporal epilepsy (ADTLE) is a syndrome characterized by ictal auditory phenomena suggesting a lateral… 
2007
2007
Absence of mutations in the LGI1 receptor ADAM22 gene in autosomal dominant lateral temporal epilepsy
Review
2005
Review
2005
Genetics of Idiopathic Epilepsies
Summary:  Purpose: To search for clues to molecular genetics of common idiopathic epilepsy syndromes. Genetic defects have been… 
2004
2004
Autosomal Dominant Lateral Temporal Epilepsy: Two Families with Novel Mutations in the LGI1 Gene
Summary:  Purpose: Mutations in the leucine rich, glioma inactivated gene (LGI1) were recently described in a small number of… 
Highly Cited
2003
Highly Cited
2003
Epilepsy with auditory features: A LGI1 gene mutation suggests a loss‐of‐function mechanism
Autosomal dominant partial epilepsy with auditory features (ADPEAF) is a genetically heterogeneous disorder. Some patients… 
2003
2003
Expression of the LGI1 gene product in astrocytic gliomas: downregulation with malignant progression
Loss of heterozygosity in the long arm of chromosome 10q is a frequent event in gliomas. It may involve the LGI1/epitempin gene… 
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