LGI1 protein, human

Known as: Leucine-Rich Glioma-Inactivated Protein 1, leucine-rich, glioma-inactivated 1 protein, human, BA512J3.1 
Predominantly expressed in neural tissues and encoded by human LGI1 Gene, a 557-amino acid 64-kD precursor yields mature 60-kD putative tumor… (More)

Topic mentions per year

Topic mentions per year

1998-2018
010203019982018

Papers overview

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Highly Cited
2013
Highly Cited
2013
More than 30 mutations in LGI1, a secreted neuronal protein, have been reported with autosomal dominant lateral temporal lobe… (More)
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Highly Cited
2010
Highly Cited
2010
BACKGROUND Voltage-gated potassium channels are thought to be the target of antibodies associated with limbic encephalitis… (More)
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Highly Cited
2010
Highly Cited
2010
Epilepsy is a devastating and poorly understood disease. Mutations in a secreted neuronal protein, leucine-rich glioma… (More)
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2010
2010
Mutations in leucine-rich glioma inactivated (LGI1) are a genetic cause of autosomal dominant temporal lobe epilepsy with… (More)
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Highly Cited
2006
Highly Cited
2006
Abnormally synchronized synaptic transmission in the brain causes epilepsy. Most inherited forms of epilepsy result from… (More)
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Highly Cited
2005
Highly Cited
2005
Mutations in LGI1 have been linked to autosomal dominant partial epilepsy with auditory features (ADPEAF), an unusual inherited… (More)
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2004
2004
Gliomas take a number of different genetic routes in the progression to glioblastoma multiforme, a highly invasive variant that… (More)
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Highly Cited
2002
Highly Cited
2002
The epilepsies are a common, clinically heterogeneous group of disorders defined by recurrent unprovoked seizures. Here we… (More)
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Highly Cited
2002
Highly Cited
2002
Autosomal dominant lateral temporal epilepsy (EPT; OMIM 600512) is a form of epilepsy characterized by partial seizures, usually… (More)
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Highly Cited
1998
Highly Cited
1998
Loss of heterozygosity for 10q23–26 is seen in over 80% of glioblastoma multiforme tumors. We have used a positional cloning… (More)
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