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LGI1 gene

Known as: IB1099, Leucine-Rich, Glioma Inactivated 1 Gene, LEUCINE-RICH GENE, GLIOMA-INACTIVATED, 1 
This gene plays a role in neural cell function and is involved in the suppression of brain cancer.
National Institutes of Health

Related topics

Related topics

5 relations
Congenital EpilepsyInhibition of Cancer Cell GrowthLGI1 protein, humanMalignant Glioma

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LGI1 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Autosomal dominant lateral temporal epilepsy (ADLTE): Novel structural and single-nucleotide LGI1 mutations in families with predominant visual auras
2012
2012
LGI1 microdeletion in autosomal dominant lateral temporal epilepsy
Objectives: To characterize clinically and genetically a family with autosomal dominant lateral temporal epilepsy (ADLTE… 
2011
2011
LGI1 related limbic encephalitis and response to immunosuppressive therapy
Limbic encephalitis (LE) is characterized by a subacute onset of episodic memory impairment, disorientation, agitation, seizures… 
2010
2010
Evaluation of depression risk in LGI1 mutation carriers
Purpose:  Depression is the most common comorbid condition in epilepsy. The cause of this comorbidity is unknown, and could… 
2009
2009
Drug resistant ADLTE and recurrent partial status epilepticus with dysphasic features in a family with a novel LGI1mutation: electroclinical, genetic, and EEG/fMRI findings
Purpose:  We characterized a family with autosomal dominant lateral temporal epilepsy (ADLTE) whose proband presented uncommon… 
2007
2007
STRUCTURAL ANOMALY OF LEFT LATERAL TEMPORAL LOBE IN EPILEPSY DUE TO MUTATED LGI1
Autosomal dominant lateral temporal epilepsy (ADTLE) is a syndrome characterized by ictal auditory phenomena suggesting a lateral… 
Highly Cited
2004
Highly Cited
2004
A de novo LGI1 mutation in sporadic partial epilepsy with auditory features
2004
2004
Autosomal Dominant Lateral Temporal Epilepsy: Two Families with Novel Mutations in the LGI1 Gene
Summary:  Purpose: Mutations in the leucine rich, glioma inactivated gene (LGI1) were recently described in a small number of… 
2003
2003
Novel LGI1 mutation in a family with autosomal dominant partial epilepsy with auditory features
Autosomal dominant partial epilepsy with auditory features (ADPEAF) is a rare idiopathic epilepsy syndrome caused by mutations in… 
1999
1999
Skeletal dysplasias, growth retardation, reduced postnatal survival, and impaired fertility in mice lacking the SNF2/SWI2 family member ETL1
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