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LGI1 gene

Known as: IB1099, Leucine-Rich, Glioma Inactivated 1 Gene, LEUCINE-RICH GENE, GLIOMA-INACTIVATED, 1 
This gene plays a role in neural cell function and is involved in the suppression of brain cancer.
National Institutes of Health

Papers overview

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Highly Cited
2016
Highly Cited
2016
Objective: To assess the clinical relevance of a positive voltage-gated potassium channel (VGKC) test in patients lacking… Expand
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Highly Cited
2014
Highly Cited
2014
In limbic encephalitis (LE) with antibodies (Abs) to the voltage-gated potassium channel complex (VGKC), the Abs are mainly… Expand
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Highly Cited
2013
Highly Cited
2013
More than 30 mutations in LGI1, a secreted neuronal protein, have been reported with autosomal dominant lateral temporal lobe… Expand
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Highly Cited
2010
Highly Cited
2010
Antibodies that immunoprecipitate 125I-α-dendrotoxin-labelled voltage-gated potassium channels extracted from mammalian brain… Expand
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Highly Cited
2010
Highly Cited
2010
LGI1 in humans is responsible for a predisposition to autosomal dominant partial epilepsy with auditory features (ADPEAF… Expand
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Highly Cited
2009
Highly Cited
2009
Most epilepsy genes encode ion channels, but the LGI1 gene responsible for autosomal dominant partial epilepsy with auditory… Expand
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Highly Cited
2004
Highly Cited
2004
Objectives: Mutations in LGI1 cause autosomal dominant partial epilepsy with auditory features (ADPEAF), a form of familial… Expand
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Highly Cited
2003
Highly Cited
2003
PURPOSE [corrected] To describe the clinical and genetic findings of seven additional pedigrees with autosomal dominant lateral… Expand
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Highly Cited
2002
Highly Cited
2002
The epilepsies are a common, clinically heterogeneous group of disorders defined by recurrent unprovoked seizures. Here we… Expand
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Highly Cited
1998
Highly Cited
1998
Loss of heterozygosity for 10q23–26 is seen in over 80% of glioblastoma multiforme tumors. We have used a positional cloning… Expand
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