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LGI1 gene

Known as: IB1099, Leucine-Rich, Glioma Inactivated 1 Gene, LEUCINE-RICH GENE, GLIOMA-INACTIVATED, 1 
This gene plays a role in neural cell function and is involved in the suppression of brain cancer.
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2016
Highly Cited
2016
Objective: To assess the clinical relevance of a positive voltage-gated potassium channel (VGKC) test in patients lacking… Expand
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Highly Cited
2013
Highly Cited
2013
More than 30 mutations in LGI1, a secreted neuronal protein, have been reported with autosomal dominant lateral temporal lobe… Expand
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Highly Cited
2010
Highly Cited
2010
Antibodies that immunoprecipitate 125I-α-dendrotoxin-labelled voltage-gated potassium channels extracted from mammalian brain… Expand
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Highly Cited
2010
Highly Cited
2010
LGI1 in humans is responsible for a predisposition to autosomal dominant partial epilepsy with auditory features (ADPEAF… Expand
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Highly Cited
2009
Highly Cited
2009
Most epilepsy genes encode ion channels, but the LGI1 gene responsible for autosomal dominant partial epilepsy with auditory… Expand
Highly Cited
2004
Highly Cited
2004
Background and Objectives: A number of familial temporal lobe epilepsies (TLE) have been recently recognized. Mutations in LGI1… Expand
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Highly Cited
2004
Highly Cited
2004
Objectives: Mutations in LGI1 cause autosomal dominant partial epilepsy with auditory features (ADPEAF), a form of familial… Expand
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Highly Cited
2003
Highly Cited
2003
Summary:  Purpose: To describe the clinical and genetic findings of seven additional pedigrees with autosomal dominant lateral… Expand
Highly Cited
2002
Highly Cited
2002
The epilepsies are a common, clinically heterogeneous group of disorders defined by recurrent unprovoked seizures. Here we… Expand
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Highly Cited
1998
Highly Cited
1998
Loss of heterozygosity for 10q23–26 is seen in over 80% of glioblastoma multiforme tumors. We have used a positional cloning… Expand
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