Skip to search formSkip to main contentSkip to account menu

LGI1 gene

Known as: IB1099, Leucine-Rich, Glioma Inactivated 1 Gene, LEUCINE-RICH GENE, GLIOMA-INACTIVATED, 1 
This gene plays a role in neural cell function and is involved in the suppression of brain cancer.
National Institutes of Health

Related topics

Related topics

5 relations
Congenital EpilepsyInhibition of Cancer Cell GrowthLGI1 protein, humanMalignant Glioma

Narrower (1)

LGI1 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Faculty of 1000 evaluation for Genetic predisposition in anti-LGI1 and anti-NMDA receptor encephalitis.
Review
2016
Review
2016
Autoimmune Epilepsy
ABSTRACTPurpose of Review: This review presents recent developments in the clinical features, immunologic basis, and treatment… 
2016
2016
THE ANALYSIS OF LGI1 GENE EPIGENETIC ALTERATIONS BY MEANS OF POSTTRANSLATIONAL H3 HISTONE MODIFICATIONS IN MALIGNANT GLIOMAS.
Although there is a progress in understanding the causes and consequences of genetic and epigenetic changes in glioma malignant… 
2015
2015
Late diagnosis of limbic encephalitis associated with LGI1 antibodies leading to relapses
Autoimmune encephalitis has been a subject of research in the past few years; most of the cases are non-paraneoplastic and… 
2008
2008
Genetics of Autosomal Dominant Partial Epilepsy with Auditory Features (ADPEAF)
Data from 24 previously published ADPEAF families with mutations in the leucine-rich, glioma inactivated 1 gene (LGI1) were… 
2007
2007
Erratum: LGI1, a putative tumor metastasis suppressor gene, controls in vitro invasiveness and expression of matrix metalloproteinases in glioma cells through the ERK1/2 pathway (Journal of…
2005
2005
LGI1 gene mutation screening in sporadic partial epilepsy with auditory features
Partial epilepsy with auditory features occasionally segregates in families as an autosomal dominant trait. In some families… 
2004
2004
Zebrafish as a vertebrate model to study retinoic acid signalling in head mesoderm and pectoral fin development and to investigate non-ion channel epilepsies
Acknowledgments: I would like to thank my advisors, Prof. Axel Meyer and Dr. Gerrit Begemann for giving me the opportunity to… 
2004
2004
LGI 1 , a Putative Tumor Metastasis Suppressor Gene , Controls in Vitro Invasiveness and Expression of Matrix Metalloproteinases in Glioma Cells through the ERK 1 / 2 Pathway *
Gliomas take a number of different genetic routes in the progression to glioblastoma multiforme, a highly invasive variant that… 
2003
2003
No evidence for an increased malignancy risk in epilepsy caused by LGI1 mutation