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LEPR gene

Known as: OBR, Leptin Receptor Gene, LEPR 
This gene plays a role in transcriptional regulation via activation of the STAT signal transduction pathway. The gene is also involved in the… 
National Institutes of Health

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Related topics

11 relations
Cytokine Signaling ProcessDiabetes MellitusIntercellular Communication ProcessLEP gene

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LEPR wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2012
2012
Normal Leptin Expression, Lower Adipogenic Ability, Decreased Leptin Receptor and Hyposensitivity to Leptin in Adolescent Idiopathic Scoliosis
Leptin has been suggested to play a role in the etiology of Adolescent Idiopathic Scoliosis (AIS), however, the leptin levels in… 
2006
2006
Novel leptin receptor mutation in NOD/LtJ mice suppresses type 1 diabetes progression: II. Immunologic analysis.
Recently, we identified in normally type 1 diabetes-prone NOD/LtJ mice a spontaneous new leptin receptor (LEPR) mutation… 
2005
2005
AAV-mediated leptin receptor installation improves energy balance and the reproductive status of obese female Koletsky rats
2005
2005
Missense mutations in exon 4 of the porcine LEPR gene encoding extracellular domain and their association with fatness traits.
Three non-synonymous single nucleotide polymorphisms (T221C, T232A and C233T) were detected in exon 4 of the porcine leptin… 
Highly Cited
2003
Highly Cited
2003
Molecular cloning and expression of the turkey leptin receptor gene.
Review
2003
Review
2003
Role of leptin and leptin receptor in inflammation.
on october 30th, 2002, the World Health Report by the World Health Organization was launched subtitled Reducing risks, promoting… 
2003
2003
Leptin and insulin downregulate leptin receptor gene expression in chicken-derived leghorn male hepatoma cells.
In chickens, leptin is expressed mainly in the liver, where its receptor gene expression has also been reported, and in adipose… 
2002
2002
Comparison of R128Q mutations in human, ovine, and chicken leptins.
Human leptin and its R128Q mutant, as well as the R128Q mutants of ovine and chicken leptins, were prepared, expressed in… 
1999
1999
Leptin responsiveness and gene dosage for leptin receptor mutation (fa) in newborn rats.
To determine the degree to which the leptin receptor mutation (fa) influences the responsiveness to leptin during the first… 
Highly Cited
1997
Highly Cited
1997
Expression of leptin receptor mRNA (long form splice variant) in the human cerebellum
PRIMERS specific to the long isoform of leptin receptor (OB-Rb) mRNA were used in reverse transcriptaselinked polymerase chain… 
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