P. Kalra

Publications243
h-index64
Citations16,158
Highly Influential Citations389
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Interacting appetite-regulating pathways in the hypothalamic regulation of body weight.
TLDR
Multiple orexigenic and anorexigenic pathways in the hypothalamic ARN appear to represent redundancy, a characteristic of regulated biological systems to provide a "fail-safe" neural mechanism to meet an organism's constant energy needs for growth and maintenance.
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Neuropeptide Y and human pancreatic polypeptide stimulate feeding behavior in rats.
TLDR
Findings imply that neuropeptide Y, or a closely related pancreatic polypeptides-like neuropePTide, plays an important role in neural regulation of feeding behavior.
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Neuropeptide Y secretion increases in the paraventricular nucleus in association with increased appetite for food.
TLDR
Findings of intense and dynamic NPY neurosecretory activity within a discrete hypothalamic site in association with an increased drive for food consumption demonstrate that NPY release in the PVN is an important orexigenic signal for periodic eating behavior.
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Food intake elicited by central administration of orexins/hypocretins: identification of hypothalamic sites of action 1 This study was presented in part at the 28th Annual Meeting of the Society…
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Neural regulation of luteinizing hormone secretion in the rat.
TLDR
Abnormalities in periodicity, onset, duration and magnitude of the preovulatory LH discharge during middLH secretion during pubertal life are studied.
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NPY and cohorts in regulating appetite, obesity and metabolic syndrome: beneficial effects of gene therapy
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Transitory changes in plasma progestins, estradiol, and luteinizing hormone approaching ovulation in the bovine.
TLDR
Radioimmunoassay results are consistent with the hypothesis that an increase at proestrus in estradiol rather than progestins triggers the preovulatory surge of luteinizing hormone in the bovine.
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Nutritional Infertility: The Role of the Interconnected Hypothalamic Neuropeptide Y–Galanin–Opioid Network
TLDR
The current findings summarized in this review support the concept that NPY may be one of the essential messenger molecules that serve as a communication bridge between the neural processes that regulate reproduction and those that maintain energy homeostasis.
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Neuropeptide Y stimulates feeding but inhibits sexual behavior in rats.
TLDR
It is suggested that NPY selectively depresses sexual motivation in the male rat by reducing the proportion of rats showing erection or latency to initial erection and increasing the number of erections per test.
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Ghrelin and leptin pulse discharge in fed and fasted rats.
TLDR
Analysis of plasma ghrelin and leptin by sensitive radioimmunoassays showed that the two peripheral hormones are secreted in pulsatile fashion in rats consuming ad libitum rat chow, implying that a synchronous leptin restraint and gh Relin stimulus on NPYergic signaling may underlie robust appetitive drive.
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