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L 745337

Known as: L 745,337, L-745,337, L-745337 
National Institutes of Health

Related topics

Related topics

5 relations

Broader (5)

AnalgesicsAnti-Inflammatory Agents, Non-SteroidalAnti-Ulcer AgentCyclooxygenase Inhibitors

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2007
2007
Pharmacological nature of nicotine-induced contraction in the rat basilar artery: involvement of arachidonic acid metabolites.
2007
2007
Action of cyclooxygenase inhibitors and a leukotriene biosynthesis inhibitor on cisplatin-induced acute and delayed emesis in the ferret.
Cisplatin at 5 mg/kg, i.p. induced an acute (day 1) and delayed (days 2 and 3) emetic response in the ferret that was used to… 
Review
2005
Review
2005
Cyclooxygenase isoenzymes and patency of ductus arteriosus.
2002
2002
Contractile Effect of Anaphylatoxin C5a and of a Mimetic Peptide on the Human Umbilical Artery: Further Evidence for Leukocyte-Dependent Vasomotion
Reproducible and concentration-dependent contractile effects were recorded when the human umbilical artery was exposed to… 
2000
2000
Effect of the COX-2 Selective Inhibitor L-745,337 on Inflammation and Organ Prostaglandin E2 (PGE2) Levels in Adjuvant Arthritic Rats
The anti-inflammatory activity of the cyclooxygenase-2 inhibitor, L745,337, was assessed in adjuvant arthritic rats (AA). The… 
1999
1999
Isoprostanes and PGE2 production in human isolated pulmonary artery smooth muscle cells: concomitant and differential release
The isoprostanes are a group of biologically active arachidonic acid metabolites initially thought to be formed under conditions… 
1999
1999
Cyclooxygenase-independent induction of p21WAF-1/cip1, apoptosis and differentiation by L-745,337, a selective PGH synthase-2 inhibitor, and salicylate in HT-29 cells
In order to dissect out cyclooxygenase-dependent from cyclooxygenase-independent mechanisms in the antiproliferative effects of… 
Highly Cited
1998
Highly Cited
1998
Induction of cyclooxygenase-2 causes an enhancement of writhing response in mice.
1998
1998
Peptidergic and cholinergic neurons and mediators in peptone-induced gastroprotection: role of cyclooxygenase-2.
This study investigates the neural pathways, mediators, and cyclooxygenase isoenzymes involved in the gastroprotection conferred… 
1997
1997
COX-2, HO NO! Cyclooxygenase-2, heme oxygenase and nitric oxide synthase: Their role and interactions in inflammation. BIRAs Symposium, Saint Bartholomew's Hospital, London, 26 April 1996
This meeting, chaired by Professor Willoughby, was organised at short notice and yet pulled a full house and, at times standing… 
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