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Iron Oxide Nanoparticles for Magnetically-Guided and Magnetically-Responsive Drug Delivery

In this review, this last case, an alternating magnetic field can modify the structure of the colloid, thereby providing spatial and temporal control over drug release.
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Assessment of diclofenac permeation with different formulations: anti-inflammatory study of a selected formula.

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Selective cyclooxygenase-2 (COX-2) inhibitors reduce anti-Mycobacterium antibodies in adjuvant arthritic rats.

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Pharmacokinetics of sulfamethoxazole and trimethoprim association in hens.

The apparently slower elimination of TMP from serum following oral administration should provide an extended duration of the synergistic antibacterial effect when this route of administration is employed and resulted in an appropriate synergistic ratio (S/T ratio = 20:1) of the drugs in the serum.
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Rapid Human Skin Permeation and Topical Anaesthetic Activity of a New Amethocaine Microemulsion

The results suggest that microemulsion could be a valuable formula for improving amethocaine permeation and thus bringing rapid pain relief.
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Age-dependent enzymuria, proteinuria and changes in renal blood flow and glomerular filtration rate in rats

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Effect of Topically Applied Cyclooxygenase-2-Selective Inhibitors on Arachidonic Acid- and Tetradecanoylphorbol Acetate-Induced Dermal Inflammation in the Mouse

COX-2-selective inhibitors showed lower topical anti-inflammatory activity than indomethacin or zileuton in AA and TPA-induced increase in MPO.
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Effect of magnet implant on iron biodistribution of Fe@C nanoparticles in the mouse

The results indicate that mice with an inflammatory compartment are suitable for primary screening of different NP types and show that selective biodistribution is greater when a low dose of NP was used and that distribution in the target organ was increased by the magnetic field.
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Thermal Hyperalgesia and Light Touch Allodynia After Intradermal Mycobacterium butyricum Administration in Rat

It is demonstrated that hyperalgesia, but not allodynia, appeared after Mycobacterium butyricum in both groups, suggesting that changes in sensitivity were not merely the result of local hypersensitivity of the inflamed tissue, but may also be due to alterations in nociception in the central nervous system.
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In vitro characterization and in vivo analgesic and anti-allodynic activity of PLGA-bupivacaine nanoparticles

A non-Fickian mechanism was concluded to be involved in the release of bupivacaine from the nanoparticles, taking into account the value of the diffusional exponent obtained (n = 0.95).
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