Kynurenine

Known as: Benzenebutanoic acid, alpha,2-diamino-gamma-oxo-, Kynurenin, Kynurenine [Chemical/Ingredient] 
 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2012
Review
2012
The essential amino acid tryptophan is not only a precursor of serotonin but is also degraded to several other neuroactive… (More)
  • figure 1
  • figure 2
  • figure 3
  • table 1
  • figure 4
Is this relevant?
Review
2011
Review
2011
In the field of depression, inflammation-associated depression stands up as an exception since its causal factors are obvious and… (More)
Is this relevant?
Review
2011
Review
2011
There is developing interest in the role of the kynurenines in the immune function. A considerable amount of evidence has… (More)
  • figure 1
  • figure 2
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2010
Highly Cited
2010
Control of blood vessel tone is central to vascular homeostasis. Here we show that metabolism of tryptophan to kynurenine by… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 14
Is this relevant?
Highly Cited
2007
Highly Cited
2007
The kynurenine pathway is a major route of L-tryptophan catabolism producing neuroactive metabolites implicated in… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2007
Highly Cited
2007
The neurodegeneration hypothesis proposed major depression as a consequence of the imbalance between neuroprotective and… (More)
Is this relevant?
Review
2004
Review
2004
In mammalian cells, the essential amino acid tryptophan is degraded primarily by the kynurenine pathway, a cascade of enzymatic… (More)
Is this relevant?
Review
2002
Review
2002
The kynurenine pathway is the main pathway for tryptophan metabolism. It generates compounds that can modulate activity at… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Review
2002
Review
2002
Degradation of the essential amino acid tryptophan along the kynurenine pathway (KP) yields several neuroactive intermediates… (More)
  • figure 1
  • table 1
Is this relevant?
Highly Cited
1982
Highly Cited
1982
Kynurenine and related compounds are endogenous metabolites of tryptophan which have previously been found to be convulsant in… (More)
Is this relevant?