3-hydroxykynurenine

Known as: 3-Hydroxy-DL-kynurenine, benzenebutanoic acid, alpha,2-diamino-3-hydroxy-gamma-oxo-, alpha,2-Diamino-3-hydroxy-gamma-oxobenzenebutanoic Acid 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1952-2017
010203019522016

Papers overview

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Highly Cited
2009
Highly Cited
2009
Vitamins B2 and B6 serve as cofactors in enzymatic reactions involved in tryptophan and homocysteine metabolism. Plasma… (More)
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Highly Cited
2006
Highly Cited
2006
The brain levels of the endogenous excitotoxin quinolinic acid (QUIN) and its bioprecursor, the free radical generator 3… (More)
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Highly Cited
2002
Highly Cited
2002
Indoleamine 2,3-dioxygenase (IDO), an enzyme involved in the catabolism of tryptophan, is expressed in certain cells and tissues… (More)
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Highly Cited
2001
Highly Cited
2001
BACKGROUND Metabolites of the kynurenine pathway of tryptophan degradation may play a role in the pathogenesis of several human… (More)
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Highly Cited
1998
Highly Cited
1998
3-Hydroxykynurenine (3-HK) is a potential endogenous neurotoxin whose increased levels have been described in several… (More)
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Highly Cited
1996
Highly Cited
1996
3-Hydroxykynurenine (3-HK) is a tryptophan metabolite whose level in the brain is markedly elevated under several pathological… (More)
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1996
1996
3-Hydroxykynurenine (3-HK) is a tryptophan metabolite whose level in the brain is elevated under several pathological states… (More)
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1994
1994
Experiments have been conducted on various aspects of the biosynthetic pathway leading to the formation of 3-hydroxykynurenine… (More)
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1992
1992
Concentrations of the neurotoxic tryptophan metabolite, 3-hydroxykynurenine, were determined in brain tissue taken post-mortem… (More)
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1989
1989
The toxicity of 3-hydroxykynurenine (3HK), an endogenous tryptophan metabolite which is markedly elevated in rat CNS tissue as a… (More)
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