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Ku 0063794

Known as: Ku-63794, Ku 63794, Ku -0063794 
 
National Institutes of Health

Papers overview

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2016
2016
Target of rapamycin (TOR), a master sensor for growth factors and nutrition availability in eukaryotic species, is a specific… Expand
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Highly Cited
2015
Highly Cited
2015
Target of rapamycin (TOR) acts as a master regulator to control cell growth by integrating nutrient, energy, and growth factors… Expand
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2014
2014
ABSTRACT Since its introduction in New York City, NY, in 1999, West Nile virus (WNV) has spread to all 48 contiguous states of… Expand
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Highly Cited
2013
Highly Cited
2013
The mTOR pathway is aberrantly stimulated in many cancer cells, including pancreatic ductal adenocarcinoma (PDAC), and thus it is… Expand
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2012
2012
Background: The molecular mechanisms that regulate the hippo-like Mst1 protein kinase remain elusive. Results: PI3-kinase and… Expand
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Highly Cited
2012
Highly Cited
2012
Background: Several new ATP-competitive mTOR inhibitors have been described, but their kinome-wide selectivity profiles have not… Expand
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Highly Cited
2012
Highly Cited
2012
Background:Combined targeting of MAPK and PI3K signalling pathways may be necessary for optimal therapeutic activity in cancer… Expand
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2012
2012
T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive malignant hematological disorder arising in the thymus from T-cell… Expand
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2011
2011
Mechanical signals can inactivate glycogen synthase kinase 3β (GSK3β), resulting in stabilization of β-catenin. This signaling… Expand
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Highly Cited
2009
Highly Cited
2009
mTOR (mammalian target of rapamycin) stimulates cell growth by phosphorylating and promoting activation of AGC (protein kinase A… Expand
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