Skip to search formSkip to main contentSkip to account menu

Ketotifen

Known as: 10H-Benzo(4,5)cyclohepta(1,2-b)thiophen-10-one, 4,9-dihydro-4-(1-methyl-4-piperidinylidene)-, Ketotifene, Ketotiphen 
A cycloheptathiophene derivative with anti-allergic activity. Ketotifen selectively blocks histamine (H1) receptors and prevents the typical symptoms… 
National Institutes of Health

Related topics

Related topics

19 relations

Broader (3)

Anti-Allergic AgentsAntipruriticsHistamine H1 Antagonists
Drug AllergyHistamine H1 Receptor Antagonists [MoA]In BloodKetotifen 0.25 MG/ML Ophthalmic Solution

Narrower (4)

Ketotifen FumarateZaditenZaditornorketotifen

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
Mast cell stabilizing effects of Sphaeranthus indicus.
Highly Cited
2006
Highly Cited
2006
Anthrax Lethal Toxin Induces Ketotifen-Sensitive Intradermal Vascular Leakage in Certain Inbred Mice
ABSTRACT Bacillus anthracis lethal toxin (LT) is a bipartite toxin composed of protective antigen (PA) and lethal factor (LF… 
2000
2000
A new model of allergic rhinitis in rats by topical sensitization and evaluation of H(1)-receptor antagonists.
Highly Cited
1999
Highly Cited
1999
Determination of some antihistaminic drugs by atomic absorption spectrometry and colorimetric methods.
1998
1998
Synthesis and antiallergic activity of pyridothienopyrimidines.
1994
1994
Role of 5-HT3 receptors and afferent fibers in the effects of mast cell degranulation on colonic motility in rats.
Highly Cited
1993
Highly Cited
1993
Proconvulsant effect of ketotifen, a histamine H1 antagonist, confirmed by the use of d-chlorpheniramine with monitoring electroencephalography.
Ketotifen produced seizures in a 5-year-old boy with secondary generalized epilepsy (SGE) and allergic rhinitis. To confirm that… 
Highly Cited
1985
Highly Cited
1985
Terbutaline-induced desensitization of human lymphocyte beta 2-adrenoceptors. Accelerated restoration of beta-adrenoceptor responsiveness by prednisone and ketotifen.
We investigated, in 36 healthy volunteers, the effects of prednisone and ketotifen on recovery of lymphocyte beta 2-adrenoceptor… 
Highly Cited
1984
Highly Cited
1984
Inhibition by azelastine of nonallergic histamine release from rat peritoneal mast cells.
1978
1978
The Protective Effect of Ketotifen in Bronchial Asthma
Thirty-six patients with confirmed allergic bronchial asthma were divided into 3 parallel groups and treated with ketotifen 1 mg… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)