Ketotifen

Known as: 10H-Benzo(4,5)cyclohepta(1,2-b)thiophen-10-one, 4,9-dihydro-4-(1-methyl-4-piperidinylidene)-, Ketotifene, Ketotiphen 
A cycloheptathiophene derivative with anti-allergic activity. Ketotifen selectively blocks histamine (H1) receptors and prevents the typical symptoms… (More)
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
BACKGROUND Mast cell activation is thought to be involved in visceral hypersensitivity, one of the main characteristics of the… (More)
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Highly Cited
2006
Highly Cited
2006
Despite intensive research, the mechanisms by which vesicular systems deliver drugs into intact skin are not yet fully understood… (More)
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Highly Cited
2005
Highly Cited
2005
s of papers SERUM BINDING OF DRUGS TO Oft-ACID GLYCOPROTEIN F. Belpaire . For many basic drugs, c41-acid @lycoprotein (~%-AGP) is… (More)
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Highly Cited
1995
Highly Cited
1995
Recent studies have suggested that nitric oxide (NO.), the product of nitric oxide synthase in inflammatory cells, may play a… (More)
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Highly Cited
1993
Highly Cited
1993
Recent work has demonstrated that inhibition of nitric oxide production with various nitric oxide synthesis inhibitors (L-NAME, L… (More)
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1992
1992
The effects of ketotifen, a 'mast cell stabiliser,' on two models of experimental colitis were examined. The inflammatory… (More)
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1992
1992
To evaluate the prophylactic effect of ketotifen against the onset of asthma we selected 121 infants with atopic dermatitis… (More)
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1991
1991
PURPOSE Eosinophilic gastroenteritis (EG) is a rare condition of unknown etiology characterized by vomiting, diarrhea, protein… (More)
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1987
1987
Based on (1) the large numbers of mast cells present in neurofibromas, (2) the possibility that these mast cells contribute… (More)
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1980
1980
The efficacy and adverse effects of ketotifen 1 mg twice daily and 2 mg twice daily were compared with placebo in 50 patients… (More)
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