Phenylethanoid glycosides in plants: structure and biological activity.
- C. Jiménez, R. Riguera
- ChemistryNatural product reports (Print)
- 1994
Development and brain delivery of chitosan-PEG nanoparticles functionalized with the monoclonal antibody OX26.
- Y. Aktaş, M. Yemisci, P. Couvreur
- Biology, ChemistryBioconjugate chemistry
- 20 October 2005
Findings indicate that this novel targeted nanoparticulate drug delivery system was able to translocate into the brain tissue after iv administration, and these novel nanoparticles are promising carriers for the transport of the anticaspase peptide Z-DEVD-FMK into thebrain.
dd-diketopiperazines: antibiotics active against Vibrio anguillarum isolated from marine bacteria associated with cultures of Pecten maximus.
- F. Fdhila, V. Vázquez, J. R. Sánchez, R. Riguera
- ChemistryJournal of Natural Products
- 17 September 2003
This is the first time a series of dd-diketopiperazines has been isolated from a single natural source and their inhibitory activity against V. anguillarum is described.
NMR methods for unravelling the spectra of complex mixtures.
- R. Novoa-Carballal, E. Fernandez-Megia, C. Jiménez, R. Riguera
- ChemistryNatural product reports (Print)
- 2011
The main methods for the simplification of the NMR of complex mixtures by selective attenuation/suppression of the signals of certain components are presented. The application of relaxation,…
The Structures and Stereochemistry of Cytotoxic Sesquiterpene Quinones from Dactylospongia elegans.
- Jaime Rodríguez, E. Quiñoá, R. Riguera, B. M. Peters, L. Abrell, P. Crews
- Chemistry
- 1 December 1992
The assignment of absolute configuration by NMR
- J. Seco, E. Quiñoá, R. Riguera
- Chemistry
- 14 January 2004
The application of (S)-1,10-binaphthyl-2,20-diol as NMR chiral solvating agent (CSA) for omeprazole, and three of its analogs (lanso-, panto-, and rabe-prazole) was investigated. The formation of…
A Nanomedicine Transports a Peptide Caspase-3 Inhibitor across the Blood–Brain Barrier and Provides Neuroprotection
- H. Karatas, Y. Aktaş, T. Dalkara
- Biology, ChemistryJournal of Neuroscience
- 4 November 2009
A nanocarrier system that can transfer chitosan nanospheres loaded with Z-DEVD-FMK, a relatively specific caspase-3 inhibitor, across the blood–brain barrier is presented and opens new and exciting opportunities for brain delivery of biologically active peptides that are useful for the treatment of CNS disorders.
A practical guide for the assignment of the absolute configuration of alcohols, amines and carboxylic acids by NMR
- J. Seco, E. Quiñoá, R. Riguera
- Chemistry
- 26 November 2001
Determining the absolute stereochemistry of secondary/secondary diols by 1H NMR: basis and applications.
- F. Freire, J. Seco, E. Quiñoá, R. Riguera
- ChemistryJournal of Organic Chemistry
- 12 April 2005
Experimental data and theoretical calculations indicate that in these bis-MPA esters, the experimental delta deltaRS values are the result of the contribution of the shielding/deshielding effects produced by the two MPA units that combine according to the actual stereochemistry of the diol.
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