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Ketotifen Fumarate
Known as:
Fumarate, Ketotifen
, 10H-Benzo(4,5)cyclohepta(1,2-b)thiophen-10-one, 4,9-dihydro-4-(1-methyl-4-piperidinylidene)-,(E)-2-butenedioate(1:1)
, 4-(1-Methyl-4-piperidylidene)-4H-benzo[4,5]cyclohepta[1,2-b] thiophen-10(9H)-one hydrogen fumarate
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The fumarate salt of ketotifen, a cycloheptathiophene derivative with anti-allergic activity. Ketotifen selectively blocks histamine (H1) receptors…
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National Institutes of Health
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Related topics
Related topics
8 relations
Drug Allergy
Histamine H1 Receptor Antagonists [MoA]
Ketotifen
Ketotifen 0.25 MG/ML Ophthalmic Solution
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Narrower (2)
Zaditen
Zaditor
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2014
Highly Cited
2014
Analysis of release kinetics of ocular therapeutics from drug releasing contact lenses: Best methods and practices to advance the field.
A. Tieppo
,
Aarika C Boggs
,
P. Pourjavad
,
M. Byrne
Contact lens & anterior eye : the journal of the…
2014
Corpus ID: 21138354
2013
2013
Ketotifen, a mast cell blocker improves sperm motility in asthenospermic infertile men
N. Saharkhiz
,
R. Nikbakht
,
M. Hemadi
Journal of Human Reproductive Sciences
2013
Corpus ID: 5463154
AIM: This study aimed to evaluate the efficacy of ketotifen on sperm motility of asthenospermic infertile men. SETTING AND DESIGN…
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Highly Cited
2011
Highly Cited
2011
In vitro and in vivo evaluation of ketotifen fumarate-loaded silicone hydrogel contact lenses for ocular drug delivery
Jinku Xu
,
Xinsong Li
,
Fu-qian Sun
Drug Delivery
2011
Corpus ID: 1168318
The purpose of this work was to evaluate the usefulness of silicone hydrogel contact lenses loaded with ketotifen fumarate for…
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Highly Cited
2010
Highly Cited
2010
Design and evaluation of transdermal drug delivery of ketotifen fumarate
A. Shivaraj
,
R. Selvam
,
T. Mani
,
T. Sivakumar
2010
Corpus ID: 97006890
The purpose of this research work was to develop and evaluate matrix-type transdermal therapeutic system containing Ketotifen…
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2010
2010
Formulation of Ketotifen Fumarate Fast-Melt Granulation Sublingual Tablet
S. Tayel
,
I. I. Soliman
,
Dina Louis
AAPS PharmSciTech
2010
Corpus ID: 1783144
The purpose of this study was to prepare sublingual tablets, containing the antiasthmatic drug ketotifen fumarate which suffers…
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Highly Cited
2010
Highly Cited
2010
The mast cell stabilizer ketotifen fumarate lessens contracture severity and myofibroblast hyperplasia: a study of a rabbit model of posttraumatic joint contractures.
M. Monument
,
D. Hart
,
A. Befus
,
P. Salo
,
Mei Zhang
,
K. Hildebrand
Journal of Bone and Joint Surgery. American…
2010
Corpus ID: 11561592
BACKGROUND The propensity of joints to become stiff after trauma is widely appreciated, and the joint capsule is commonly…
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Highly Cited
2003
Highly Cited
2003
In vitro uptake and release studies of ocular pharmaceutical agents by silicon-containing and p-HEMA hydrogel contact lens materials.
C. Karlgard
,
N. Wong
,
Lyndon Jones
,
Christine Moresoli
International journal of pharmaceutics
2003
Corpus ID: 46029441
2000
2000
A forced choice comfort study of olopatadine hydrochloride 0.1% versus ketotifen fumarate 0.05%.
M. N. Artal
,
José Domingo Luna
,
M. Discepola
Acta ophthalmologica Scandinavica. Supplement
2000
Corpus ID: 19327508
PURPOSE To compare the ocular comfort of two ophthalmic anti-allergic agents: olopatadine hydrochloride 0.1% and ketotifen…
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1998
1998
Role of mast cells, neutrophils and nitric oxide in endotoxin‐induced damage to the neonatal rat colon
J. F. Brown
,
K A Chafee
,
B. Tepperman
British Journal of Pharmacology
1998
Corpus ID: 40425688
The mechanisms involved in mediating bacterial endotoxin lipopolysaccharide (LPS)‐induced injury in the colon of neonatal rat…
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Highly Cited
1993
Highly Cited
1993
A controlled multiphase trial of ketotifen to minimize neurofibroma-associated pain and itching.
V. Riccardi
Archives of Dermatology
1993
Corpus ID: 25454064
BACKGROUND AND DESIGN Based on potential contributions of mast cells to neurofibroma-associated itching, pain, and tenderness…
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