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Ketotifen Fumarate

Known as: Fumarate, Ketotifen, 10H-Benzo(4,5)cyclohepta(1,2-b)thiophen-10-one, 4,9-dihydro-4-(1-methyl-4-piperidinylidene)-,(E)-2-butenedioate(1:1), 4-(1-Methyl-4-piperidylidene)-4H-benzo[4,5]cyclohepta[1,2-b] thiophen-10(9H)-one hydrogen fumarate 
The fumarate salt of ketotifen, a cycloheptathiophene derivative with anti-allergic activity. Ketotifen selectively blocks histamine (H1) receptors… 
National Institutes of Health

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Related topics

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Drug AllergyHistamine H1 Receptor Antagonists [MoA]KetotifenKetotifen 0.25 MG/ML Ophthalmic Solution

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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2007
2007
Establishment of an allergic rhinitis model in mice for the evaluation of nasal symptoms.
2005
2005
ORIGINAL ARTICLE Effect of Ketotifen Fumarate, Olopatadine, and Levocabastine on Ocular Active Anaphylaxis in the Guinea Pig and Ocular Immediate Hypersensitivity in the Albino Rat
Purpose: To study the effects of ketotifen fumarate, olopatadine, and levocabastine on ocular active anaphylaxis in guinea pigs… 
2004
2004
Efficacy and safety of single‐ and multiple‐dose ketotifen fumarate 0.025% ophthalmic solution in a pediatric population
Allergic conjunctivitis can seriously disrupt children's daily activities. This study assessed the efficacy (onset and duration… 
2003
2003
Ketotifen fumarate and olopatadine hydrochloride in the treatment of allergic conjunctivitis: A real-world comparison of efficacy and ocular comfort
This 3-week prospective, randomized, double-masked, parallel-group study compared ketotifen fumarate 0.025% ophthalmic solution… 
2002
2002
Single dose of ketotifen fumarate .025% vs 2 weeks of cromolyn sodium 4% for allergic conjunctivitis
This single-masked, contralateral-eye, active-controlled allergen-challenge study compared ketotifen fumarate .025% and cromolyn… 
2002
2002
Ketotifen Fumarate Treatment of Superior Limbic Keratoconjunctivitis
Purpose. To report the effect of topically applied ketotifen fumarate in the treatment of superior limbic keratoconjunctivitis… 
2002
2002
Ocular tolerability and safety of ketotifen fumarate ophthalmic solution
Ketotifen fumarate, formulated for the treatment of allergic conjunctivitis, is a histamine H1-receptor antagonist, mast cell… 
2000
2000
The Skin Permeation Mechanism of Ketotifen: Evaluation of Permeation Pathways and Barrier Components in the Strat Corneum
To evaluate the pathways and barrier components in the stratum corneum (SC) for the permeation of ketotifen, the effect of… 
1994
1994
Contact dermatitis from ketotifen fumarate eyedrops
A 37-year-old man with allergic conjunctivitis had been treated with ketotifen fumarate (KF), ofloxacin, fluoromethoron and… 
1990
1990
Effect of ketotifen on antigen-induced interleukin 2 (IL-2) responsiveness in lymphocytes from patients with atopic dermatitis and/or bronchial asthma.
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