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KT 362

Known as: 1,5-Benzothiazepine, 5-(3-((2-(3,4-dimethoxyphenyl)ethyl)amino)-1-oxopropyl)-2,3,4,5-tetrahydro-, (E)-2-butenedioate (1:1), KT-362 
National Institutes of Health

Related topics

Related topics

4 relations

Broader (4)

Anti-Arrhythmia AgentsCalcium Channel BlockersThiazepinesVasodilator Agents

Papers overview

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2004
2004
Effects of KT-362, a sarcolemmal and intracellular calcium antagonist, on calcium transients of cultured neonatal rat ventricular cells: A comparison with gallopamil and ryanodine
SummaryWe evaluated the effects of KT-362 (5-[3-([2-(3,4-dimethoxyphenyl)-ethyl]amino)-1-oxopropyl]-2,3,4,5-tetrahydro-1,5… 
1991
1991
Comparative Cardiac Effects of KT‐362 and Verapamil in Isolated Hearts—Correlation to Calcium Channel Current Depression
Summary: Direct cardiac effects of KT-362 (5-[3[[-2-(3,4-dimethoxyphenyl)-ethyl]amino]-1-oxopropyl]-2,3,4,5-tetrahydro-1,5… 
1990
1990
Effects of KT-362, a new calcium release blocker, on vascular selectivity and hemodynamic actions in anesthetized dogs.
Pharmacological properties of 5-(3-((2-(3,4-dimethoxyphenyl)ethyl)-amino)-1- oxopropyl)-2,3,4,5-tetrahydro-1,5-benzothiazepine… 
1990
1990
Augmented Vascular Relaxation to KT‐362 in Diabetic Rat Aorta: Comparison to Diltiazem
Diabetes-induced alterations in the vasorelaxant properties of the calcium entry blocker diltiazem and a new putative vascular… 
1989
1989
Effect of KT‐362, a Putative Intracellular Calcium Antagonist, on Norepinephrine‐Induced Contractions and Inositol Monophosphate Accumulation in Canine Femoral Artery
Summary: The purpose of the present study was to determine if the intracellular calcium antagonist, KT-362, inhibits… 
1989
1989
Collateral Blood Flow Following Acute Coronary Artery Occlusion: Comparison of a New Intracellular Calcium Antagonist (KT‐362) and Diltiazem
The effects of a new intracellular calcium antagonist, KT-362 (150 and 300 μg/kg per min), on hemodynamics and collateral… 
1989
1989
Reduction of myocardial ischemia-reperfusion injury by KT-362, a new intracellular calcium antagonist in anesthetized dogs.
The effects of a new intracellular calcium antagonist, KT-362 (5-[3-[[2-(3,4-dimethoxyphenyl)-ethyl]amino]-1-oxopropyl]- 2,3,4,5… 
1989
1989
Effects of KT-362, a new Na and Ca influx and Ca release inhibitor, on canine ventricular arrhythmias.
Antiarrhythmic effects of the new drug KT-362, which was reported to suppress Na and Ca currents of cardiac cells and also to… 
1988
1988
Electrophysiological effects of KT-362, a new antiarrhythmic agent with vasodilating action, on isolated guinea pig ventricular muscle.
The effects of KT-362, a newly synthesized vasodilating and antiarrhythmic agent, on transmembrane action potentials were… 
1988
1988
Hemodynamic and electrocardiographic actions of the new intracellular calcium antagonist, KT-362, in the conscious dog.
Effects of the intracellular calcium antagonist, KT-362, on systemic and coronary hemodynamics and the electrocardiogram were… 
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