KNSTRN gene

Known as: KNSTRN, SMALL KINETOCHORE-ASSOCIATED PROTEIN, kinetochore-localized astrin/SPAG5 binding protein 
This gene plays a role in both mitotic spindle formation and chromosome segregation.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1998-2017
02419982017

Papers overview

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2017
2017
Human chromosomes are captured along microtubule walls (lateral attachment) and then tethered to microtubule-ends (end-on… (More)
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2016
2016
Accurate chromosome segregation during cell division is crucial for propagating life and protects from cellular transformation… (More)
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2014
2014
Here we report the discovery of recurrent mutations concentrated at an ultraviolet signature hotspot in KNSTRN, which encodes a… (More)
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2012
2012
Mitotic chromosome segregation is orchestrated by the dynamic interaction of spindle microtubules with the kinetochore. Although… (More)
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2011
2011
Astrin is a mitotic spindle-associated protein required for the correct alignment of all chromosomes at the metaphase plate… (More)
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2011
2011
Adhesion and degranulation promoting adapter protein (ADAP) is a multifunctional hematopoietic adapter protein that regulates TCR… (More)
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2009
2009
The spindle assembly checkpoint (SAC) controls the anaphase onset by preventing premature chromosome segregation until bipolar… (More)
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2009
2009
The cytosolic adaptor molecule SKAP-HOM, similar to the T cell-specific homologue SKAP55, interacts directly with ADAP, and both… (More)
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2005
2005
SKAP-HOM is a cytosolic adaptor protein representing a specific substrate for the Src family protein tyrosine kinase Fyn… (More)
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1998
1998
A recombinant GST-Fyn-SH2 domain was used to purify proteins from lysates of pervanadate treated EL4 cells. N-terminal sequencing… (More)
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