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KNSTRN gene

Known as: KNSTRN, SMALL KINETOCHORE-ASSOCIATED PROTEIN, kinetochore-localized astrin/SPAG5 binding protein 
This gene plays a role in both mitotic spindle formation and chromosome segregation.
National Institutes of Health

Papers overview

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2017
2017
Human chromosomes are captured along microtubule walls (lateral attachment) and then tethered to microtubule-ends (end-on… Expand
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2016
2016
The Astrin/SKAP complex plays important roles in mitotic chromosome alignment and centrosome integrity, but previous work found… Expand
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2015
2015
Institute Innovation Award. Theresa H.M. Keegan, Susan M. Swetter, Li Tao, John B. Sunwoo and Christina A. Clarke Department of… Expand
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Highly Cited
2014
Highly Cited
2014
Here we report the discovery of recurrent mutations concentrated at an ultraviolet signature hotspot in KNSTRN, which encodes a… Expand
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2012
2012
Chromosome segregation in mitosis is orchestrated by the dynamic interactions between the kinetochore and spindle microtubules… Expand
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2011
2011
Adhesion and degranulation promoting adapter protein (ADAP) is a multifunctional hematopoietic adapter protein that regulates TCR… Expand
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Highly Cited
2011
Highly Cited
2011
Astrin is a mitotic spindle-associated protein required for the correct alignment of all chromosomes at the metaphase plate… Expand
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Highly Cited
2010
Highly Cited
2010
Localization of the spindle and kinetochore proteins Astrin, SKAP, and LC8 is antagonized by Aurora B so that they target… Expand
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2009
2009
The spindle assembly checkpoint (SAC) controls the anaphase onset by preventing premature chromosome segregation until bipolar… Expand
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1998
1998
A recombinant GST-Fyn-SH2 domain was used to purify proteins from lysates of pervanadate treated EL4 cells. N-terminal sequencing… Expand
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