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KN 92

Known as: KN-92 
National Institutes of Health

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2 relations

Broader (2)

BenzylaminesSulfonamides

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Apoptosis induced by NAD depletion is inhibited by KN-93 in a CaMKII-independent manner.
2011
2011
Reducing the Late Sodium Current Improves Cardiac Function during Sodium Pump Inhibition by Ouabain
Inhibition by cardiac glycosides of Na+, K+-ATPase reduces sodium efflux from myocytes and may lead to Na+ and Ca2+ overload and… 
2007
2007
KN-93, a specific inhibitor of CaMKII inhibits human hepatic stellate cell proliferation in vitro.
AIM To investigate the effects of KN-93, a CaMKII selective inhibitor on cell proliferation and the expression of p53 or p21… 
Highly Cited
2005
Highly Cited
2005
Pharmacological interactions between calcium/calmodulin-dependent kinase II α and TRPV1 receptors in rat trigeminal sensory neurons
2005
2005
G 1 Cell Cycle Arrest and Apoptosis Are Induced in NIH 3 T 3 Cells by KN-93 , an Inhibitor of CaMK-lI ( the Multifunctional Ca 2 / CaM Kinase ) 1
Abstrad CaMK-II (the type II multifundional Ca2’/calmodulin kinase) is a ubiquitous serine/threonine protein kinase that is… 
2003
2003
Calcium/calmodulin‐dependent kinase II is involved in the facilitating effect of clozapine on NMDA‐ and electrically evoked responses in the medial prefrontal cortical pyramidal cells
Using the method of intracellular recording in in vitro brain slices, we investigated whether calcium/calmodulin‐dependent kinase… 
Highly Cited
2002
Highly Cited
2002
Evidence that multifunctional calcium/calmodulin‐dependent protein kinase II (CaM KII) participates in the meiotic maturation of mouse oocytes
Calcium‐dependent signaling pathways are thought to be involved in the regulation of mammalian oocyte meiotic maturation. However… 
Highly Cited
2002
Highly Cited
2002
Participation of the Calcium/Calmodulin-dependent Kinases in Hydrogen Peroxide-induced IκB Phosphorylation in Human T Lymphocytes*
NF-κB is an important transcription factor that has a role in a variety of responses such as inflammation, oncogenesis, apoptosis… 
1999
1999
Biochemical and biological effects of KN-93, an inhibitor of calmodulin-dependent protein kinase II, on the initial events of mouse egg activation induced by ethanol.
Calmodulin-dependent protein kinase II (CaMKII) is transiently activated in mouse eggs by the increase in calcium that occurs… 
1999
1999
Arachidonic acid potentiates currents through Ca2+-permeable AMPA receptors by interacting with a CaMKII pathway.
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