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K-562

Known as: K562, K562 blasts 
The continuous cell line K-562 was established by Lozzio and Lozzio from the pleural effusion of a 53-year-old female with chronic myelogenous… 
National Institutes of Health

Papers overview

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Highly Cited
1999
Highly Cited
1999
Branched cationic peptides for gene delivery: role of type and number of cationic residues in formation and in vitro activity of DNA polyplexes.
To examine the suitability of synthetic peptides as DNA-binding and -compacting agents for receptor-mediated gene delivery, we… 
Highly Cited
1997
Highly Cited
1997
Sustained Activation of the Extracellular Signal-regulated Kinase/Mitogen-activated Protein Kinase Pathway Is Required for Megakaryocytic Differentiation of K562 Cells*
The extracellular signal-regulated kinase (ERK), originally identified as a participant in mitogenic signaling, has recently been… 
Highly Cited
1997
Highly Cited
1997
PDGF2/c-sis mRNA Leader Contains a Differentiation-linked Internal Ribosomal Entry Site (D-IRES)*
It has become clear that a given cell type can qualitatively and quantitatively affect the expression of the platelet-derived… 
Highly Cited
1994
Highly Cited
1994
Functional role of N-glycosylation in alpha 5 beta 1 integrin receptor. De-N-glycosylation induces dissociation or altered association of alpha 5 and beta 1 subunits and concomitant loss of…
Fibronectin (FN)-mediated cell adhesion is controlled mainly by alpha 5 beta 1 (recognizing the RGD sequence) and alpha 4 beta 1… 
Highly Cited
1992
Highly Cited
1992
Poly-N-acetyllactosaminyl O-glycans attached to leukosialin. The presence of sialyl Le(x) structures in O-glycans.
Highly Cited
1985
Highly Cited
1985
Intracellular movement of cell surface receptors after endocytosis: resialylation of asialo-transferrin receptor in human erythroleukemia cells
The intracellular movement of cell surface transferrin receptor (TfR) after internalization was studied in K562 cultured human… 
Highly Cited
1983
Highly Cited
1983
Phospholipid-sensitive Ca2+-dependent protein phosphorylation system in various types of leukemic cells from human patients and in human leukemic cell lines HL60 and K562, and its inhibition by alkyl…
Phospholipid-sensitive Ca2+-dependent protein kinase (PL-Ca-PK), its endogenous substrate proteins, and regulation of the enzyme… 
Highly Cited
1983
Highly Cited
1983
Differentiation stages of human natural killer cells in lymphoid tissues from fetal to adult life
Virtually all human granular lymphocytes expressed the HNK-1 differentiation antigen when examined in lymphoid compartments from… 
Highly Cited
1982
Highly Cited
1982
Characterization of the cytolytic reaction mechanism of the human natural killer (NK) lymphocyte: resolution into binding, programming, and killer cell-independent steps.
Various parameters of the cytolytic reaction mechanisms of the human natural killer (NK) lymphocyte were studied to characterize… 
Highly Cited
1981
Highly Cited
1981
Phenotypes of human natural killer cell populations detected with monoclonal antibodies.
In our recent studies, human natural killer (NK) cell activity was found to be decreased 2- to 4-fold after treatment of monocyte… 
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