Interleukin-5

Known as: Interleukin-5 [Chemical/Ingredient], T-Cell Replacing Factor, Interleukin 5 
A cytokine that promotes differentiation and activation of EOSINOPHILS. It also triggers activated B-LYMPHOCYTES to differentiate into IMMUNOGLOBULIN… (More)
National Institutes of Health

Papers overview

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Review
2011
Review
2011
Research has identified what can be considered a family of innate lymphoid cells (ILCs) that includes not only natural killer (NK… (More)
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Highly Cited
2004
Highly Cited
2004
BACKGROUND IL-5 is a cytokine critically involved in regulating several aspects of eosinophils including their production… (More)
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Highly Cited
2003
Highly Cited
2003
Eosinophil-derived TGF-beta has been implicated in remodeling events in asthma. We hypothesized that reduction of bronchial… (More)
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Highly Cited
1999
Highly Cited
1999
BACKGROUND The cause of persistent eosinophilia and the hypereosinophilic syndrome is unknown. Recent work suggests that in some… (More)
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Highly Cited
1997
Highly Cited
1997
Interleukin-5 (IL-5), which is produced by CD4(+) T helper 2 (Th2) cells, but not by Th1 cells, plays a key role in the… (More)
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Highly Cited
1996
Highly Cited
1996
Reversible airway hyperreactivity underlies the pathophysiology of asthma, yet the precise mediators of the response remain… (More)
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Highly Cited
1996
Highly Cited
1996
In this study, we investigate whether human inflammatory bowel disease (IBD) (ulcerative colitis and Crohn's disease) is… (More)
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Highly Cited
1995
Highly Cited
1995
Experiments were designed to study the effect of systemically administered IL-5 on local eosinophil accumulation induced by the… (More)
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Highly Cited
1992
Highly Cited
1992
In order to determine the role of CD4+ and CD8+ T-cells and of interleukin-5 (IL-5) in causing antigen-induced eosinophil… (More)
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Highly Cited
1988
Highly Cited
1988
Using a clonal culture system, we investigated the hemopoietic effects of purified recombinant IL-5 obtained from conditioned… (More)
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