Production of a B cell growth-promoting activity, (DL)BCGF, from a cloned T cell line and its assay on the BCL1 B cell tumor

@article{Swain1982ProductionOA,
  title={Production of a B cell growth-promoting activity, (DL)BCGF, from a cloned T cell line and its assay on the BCL1 B cell tumor},
  author={Susan L Swain and Richard W. Dutton},
  journal={The Journal of Experimental Medicine},
  year={1982},
  volume={156},
  pages={1821 - 1834}
}
Culture supernatants from a long-term alloreactive T cell line, the Dennert line C.C3.11.75 (DL) contain a B cell-growth-promoting activity. This activity can be assayed on normal B cells or on the in vivo BCL1 tumor line. We have called this activity (DL)BCGF. This activity can be distinguished from the T cell-replacing factor activity we had earlier found in DL supernates [(DL)TRF], which is required together with IL2 for the B cell plaque-forming cell response to erythrocyte antigens. The… CONTINUE READING

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References

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Showing 1-10 of 29 references

Activation of human monoclonal B cells with anti-Ig and T cell derived helper factor(s) and biochemical analysis of the transmembrane signaling in B cells

  • T. Kishimoto, K. Yoshizaki, +5 authors Y. Yamamura
  • 1982

Identification of a T cell-derived B cell growth factor distinct from interleukin 2.J

  • M. Howard, J. Farrar, +4 authors W. E. Paul
  • Exp. Med
  • 1982

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