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Interleukin-29

Known as: Interferon-Lambda-1, Interferon Lambda-1, Interferon Lambda 1 
Interferon lambda-1 (200 aa, ~22 kDa) is encoded by the human IFNL1 gene. This protein plays a role in both cytokine signaling and the response to… 
National Institutes of Health

Related topics

Related topics

9 relations
Antiviral ResponseCytokine GeneCytokine Receptor BindingCytokine Signaling

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Integrated analysis of microRNA-mRNA expression in A549 cells infected with influenza A viruses (IAVs) from different host species.
2019
2019
siRNA containing a unique 5-nucleotide motif acts as a quencher of IFI16-mediated innate immune response
We previously reported that small interfering RNA (siRNA) enhances DNA or DNA virus mediated-interferon (IFN)-λ1 induction… 
2016
2016
IL-28B Genetic Variants Determine the Extent of Monocyte-Induced Activation of NK Cells in Hepatitis C
Background Immuno-genetic studies suggest a functional link between NK cells and λ-IFNs. We recently showed that NK cells are… 
2015
2015
Effect of Interleukin-29 on Interferon-α Secretion by Peripheral Blood Mononuclear Cells
Objective The effect of interleukin (IL)-29, a new therapeutic agent similar to type I interferons (IFNs), on IFN-α secretion of… 
2014
2014
Regulation of interferon lambda-1 (IFNL1/IFN-λ1/IL-29) expression in human colon epithelial cells.
2013
2013
siRNA enhances DNA-mediated interferon lambda-1 response through crosstalk between RIG-I and IFI16 signalling pathway
In addition to silencing specific genes, small interfering RNA (siRNA) transfection is also associated with the non-specific… 
2009
2009
IFN-1 ( IL-29 ) inhibits GATA 3 expression and suppresses Th 2 responses in human naive and memory T cells
IFN1 (IL-29) plays a novel, emerging role in the inhibition of human Th2 responses. Here, we demonstrate that both naive and… 
Review
2006
Review
2006
Should We Inhibit Type I Interferons in Sepsis?
Vertebrates, as well as invertebrates and plants, have developed mechanisms to detect and respond to intruders ([31][1], [56][2… 
2005
2005
IL-28 A and IL-29 mediate antiproliferative and antiviral signals in intestinal epithelial cells and murine CMV infection increases colonic IL-28 A expression
Stephan Brand,* Florian Beigel,* Torsten Olszak, Kathrin Zitzmann, Sören T. Eichhorst, Jan-Michel Otte, Joachim Diebold, Helmut… 
2005
2005
The Novel Lambda-Interferons IL-28A and IL-29 Mediate Proinflammatory, Antiproliferative, and Antiviral Signals in Intestinal Epithelial Cells
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