Interleukin-29

Known as: Interferon-Lambda-1, Interferon Lambda-1, Interferon Lambda 1 
Interferon lambda-1 (200 aa, ~22 kDa) is encoded by the human IFNL1 gene. This protein plays a role in both cytokine signaling and the response to… (More)
National Institutes of Health

Papers overview

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Review
2011
Review
2011
The IL-10 family of cytokines consists of nine members: IL-10, IL-19, IL-20, IL-22, IL-24, IL-26, and the more distantly related… (More)
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Highly Cited
2011
Highly Cited
2011
Cytosolic foreign DNA is detected by pattern recognition receptors and mainly induces type I IFN production. We found that… (More)
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Review
2010
Review
2010
The discovery and initial description of the interferon-lambda (IFN-lambda) family in early 2003 opened an exciting new chapter… (More)
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2010
2010
BACKGROUND Specific differences in signaling and antiviral properties between the different Lambda-interferons, a novel group of… (More)
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2010
2010
Interleukin-29 (IL-29) is a member of the type III IFN family that has been shown to have antiviral activity and to inhibit cell… (More)
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Highly Cited
2006
Highly Cited
2006
BACKGROUND The autoimmune regulator (AIRE) gene influences thymic self-tolerance induction. In autoimmune polyendocrinopathy… (More)
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Highly Cited
2006
Highly Cited
2006
Interferon-alpha (IFN-alpha) is used for biotherapy of neuroendocrine carcinomas. The interferon-lambdas (IL-28A/B and IL-29) are… (More)
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Highly Cited
2005
Highly Cited
2005
Dendritic cells (DCs) respond to microbial infections by undergoing phenotypic maturation and by producing multiple cytokines. In… (More)
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Highly Cited
2005
Highly Cited
2005
Human cytomegalovirus virus (CMV) is a major cause of morbidity and mortality in immunocompromised individuals. Recently, a novel… (More)
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Highly Cited
2003
Highly Cited
2003
Cytokines play a critical role in modulating the innate and adaptive immune systems. Here, we have identified from the human… (More)
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