Skip to search formSkip to main contentSkip to account menu

Interferon Regulatory Factor 2

Known as: HINF-M Transcription Factor, Transcription Factor, HINF-M, IRF 2 Transcription Factor 
An interferon regulatory factor that represses transcription of TYPE I INTERFERONS and activates transcription of HISTONE H4.
National Institutes of Health

Related topics

Related topics

11 relations
IRF2 geneIRF2 wt AlleleIn BloodProcess of secretion

Narrower (1)

IRF2 protein, human

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2008
2008
IRF-2 regulates NF-kappaB activity by modulating the subcellular localization of NF-kappaB.
2006
2006
Nucleolin is involved in interferon regulatory factor-2-dependent transcriptional activation
We have previously shown that interferon regulatory factor-2 (IRF-2) is acetylated in a cell growth-dependent manner, which… 
Highly Cited
2003
Highly Cited
2003
Interferon Regulatory Factor-2 Regulates Cell Growth through Its Acetylation*
We have previously shown that interferon regulatory factor-2 (IRF-2) is acetylated by p300 and PCAF in vivo and in vitro. In this… 
Highly Cited
2003
Highly Cited
2003
Identification of HiNF-P, a Key Activator of Cell Cycle-Controlled Histone H4 Genes at the Onset of S Phase
ABSTRACT At the G1/S phase cell cycle transition, multiple histone genes are expressed to ensure that newly synthesized DNA is… 
Highly Cited
2001
Highly Cited
2001
Coactivator p300 Acetylates the Interferon Regulatory Factor-2 in U937 Cells following Phorbol Ester Treatment*
Interferon regulatory factor-2 (IRF-2) is a transcription factor of the IRF family that represses interferon-mediated gene… 
2000
2000
Molecular characterization of Celtix‐1, a bromodomain protein interacting with the transcription factor interferon regulatory factor 2
Transcriptional control at the G1/S‐phase transition of the cell cycle requires functional interactions of multimeric promoter… 
Highly Cited
2000
Highly Cited
2000
CD8(+) T cell-mediated skin disease in mice lacking IRF-2, the transcriptional attenuator of interferon-alpha/beta signaling.
The balanced action of cytokines is known to be critical for the maintenance of homeostatic immune responses. Here, we report the… 
Highly Cited
1998
Highly Cited
1998
Interferon Regulatory Factor-2 Is a Transcriptional Activator in Muscle Where It Regulates Expression of Vascular Cell Adhesion Molecule-1
Previously, we have suggested that vascular cell adhesion molecule-1 (VCAM-1) and its integrin receptor α4β1 mediate cell–cell… 
Highly Cited
1992
Highly Cited
1992
Inducible processing of interferon regulatory factor-2
PRDI-BFc and PRDI-BFi are proteins that bind specifically to a regulatory element required for virus induction of the human beta… 
Highly Cited
1989
Highly Cited
1989
Human H4 histone gene transcription requires the proliferation-specific nuclear factor HiNF-D. Auxiliary roles for HiNF-C (Sp1-like) and HiNF-A (high mobility group-like).
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)