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IRF2 gene

Known as: INTERFERON REGULATORY FACTOR 2, IRF2, Interferon Regulatory Factor 2 Gene 
This gene is involved in the repression of IRF1-activated transcription. It also plays a role in the transcriptional activation of target genes.
National Institutes of Health

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Related topics

6 relations
Homo sapiensIRF2 protein, humanInterferon Regulatory Factor 2Transcriptional Activation

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IRF2 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Generation of a common innate lymphoid cell progenitor requires interferon regulatory factor 2.
Innate lymphoid cells (ILCs), composed of heterogeneous populations of lymphoid cells, contribute critically to immune… 
2018
2018
Inhibition of Fas associated phosphatase 1 (Fap1) facilitates apoptosis of colon cancer stem cells and enhances the effects of oxaliplatin
Fas associated phosphatase 1 (Fap1) is a ubiquitously expressed protein tyrosine phosphatase. Fap1 substrates include Fas and… 
2014
2014
Fairfax upon Monocyte Gene Expression Innate Immune Activity Conditions the Effect of Regulatory Variants
, (2014); 343 Science et al. Benjamin P. Fairfax upon Monocyte Gene Expression Innate Immune Activity Conditions the Effect of… 
Review
2009
Review
2009
Analysis of loss of heterozygosity on chromosome 4q in hepatocellular carcinoma using high-throughput SNP array.
To identify tumour suppressor genes (TSGs) associated with hepatocellular carcinoma (HCC) on chromosome 4q using a high… 
2007
2007
Translational control of the interferon regulatory factor 2 mRNA by IRES element
Translational control represents an important mode of regulation of gene expression under stress conditions. We have studied the… 
2004
2004
Transcriptional regulation of the 230 kD bullous pemphigoid antigen (BPAG1) gene expression by interferon regulatory factor 1 (IRF1) and interferon regulatory factor 2 (IRF2) in normal human…
2002
2002
Mutation and association analysis of the interferon regulatory factor 2 gene (IRF2) with atopic dermatitis
Highly Cited
1998
Highly Cited
1998
Cell Cycle Regulation of Histone H4 Gene Transcription Requires the Oncogenic Factor IRF-2*
Histone genes display a peak in transcription in early S phase and are ideal models for cell cycle-regulated gene expression. We… 
1998
1998
PU . 1 as an essential activator for the expression of gp 91 phox gene in human peripheral neutrophils , monocytes , and B lymphocytes ( gene expression y chronic granulomatous disease )
We have reported a deficiency of a 91-kDa glycoprotein component of the phagocyte NADPH oxidase (gp91phox) in neutrophils… 
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