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Integrin alpha4beta1

Known as: Integrin Alpha4/Beta1, Very Late Antigen-4, alpha4beta1, Integrin 
Integrin alpha4beta1 is a FIBRONECTIN and VCAM-1 receptor present on LYMPHOCYTES; MONOCYTES; EOSINOPHILS; NK CELLS and thymocytes. It is involved in… 
National Institutes of Health

Related topics

Related topics

19 relations

Broader (3)

CD AntigensIntegrinsLymphocyte Homing Receptors
Cell AdhesionCell Adhesion MoleculesCell-Cell Adhesion ProcessCell-Matrix Junction

Papers overview

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Highly Cited
2001
Highly Cited
2001
Endothelial Expression of Vascular Cell Adhesion Molecule‐1 Correlates with Metastatic Pattern in Spontaneous Melanoma
Objective: Adhesive interactions between tumor cell surface receptors and endothelial cell adhesion molecules are thought to… 
Highly Cited
1996
Highly Cited
1996
In vitro accommodation of immortalized porcine endothelial cells: resistance to complement mediated lysis and down-regulation of VCAM expression induced by low concentrations of polyclonal human IgG…
The capacity of vascularized xenografts to survive in the face of normal levels of circulating antigraft antibodies and… 
Highly Cited
1996
Highly Cited
1996
Treatment of established adjuvant arthritis in rats with monoclonal antibody to CD18 and very late activation antigen‐4 integrins suppresses neutrophil and T‐lymphocyte migration to the joints and…
The migration of leucocytes from blood into the joint is a key feature of human and experimental arthritis. Adhesion molecules on… 
Highly Cited
1995
Highly Cited
1995
Role of the VLA-4 molecule in T cell costimulation. Identification of the tyrosine phosphorylation pattern induced by the ligation of VLA-4.
The very late activated Ag (VLA) molecules not only mediate T cell adhesions, but also provide costimulation in a TCR/CD3… 
Highly Cited
1995
Highly Cited
1995
Lung eosinophilia is dependent on IL-5 and the adhesion molecules CD18 and VLA-4, in a guinea-pig model.
Blood and tissue-eosinophilia is a characteristic feature of a number of disease states. In experimental animals, the intravenous… 
Highly Cited
1994
Highly Cited
1994
Nasal challenge with allergen upregulates the local expression of vascular endothelial adhesion molecules.
Highly Cited
1993
Highly Cited
1993
Regulation of human B-cell precursor adhesion to bone marrow stromal cells by cytokines that exert opposing effects on the expression of vascular cell adhesion molecule-1 (VCAM-1).
Self-renewal and differentiation of B-cell precursors is dependent on interactions with bone marrow (BM) stromal cells and… 
Highly Cited
1993
Highly Cited
1993
The efficacy of LFA-1 and VLA-4 antibody treatment in rat vascularized cardiac allograft rejection.
Highly Cited
1993
Highly Cited
1993
Vascular cell adhesion molecule-1 and VLA-4 are obligatory adhesion proteins in the heterotypic adherence between human leukemia/lymphoma cells and marrow stromal cells.
We have utilized two well-characterized human leukemia/lymphoma (LL) cell lines, UTMB-460 and CEM, to determine the role of… 
Review
1991
Review
1991
Regulation of lymphocyte traffic to mucosa-associated lymphatic tissues.
Lymphocyte recognition and binding to endothelial cells at sites where lymphocytes exit the blood is controlled by several… 
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