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Integrin alpha4beta1

Known as: Integrin Alpha4/Beta1, Very Late Antigen-4, alpha4beta1, Integrin 
Integrin alpha4beta1 is a FIBRONECTIN and VCAM-1 receptor present on LYMPHOCYTES; MONOCYTES; EOSINOPHILS; NK CELLS and thymocytes. It is involved in… 
National Institutes of Health

Related topics

Related topics

19 relations

Broader (3)

CD AntigensIntegrinsLymphocyte Homing Receptors
Cell AdhesionCell Adhesion MoleculesCell-Cell Adhesion ProcessCell-Matrix Junction

Papers overview

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Highly Cited
1999
Highly Cited
1999
Homing of human cells in the fetal sheep model: modulation by antibodies activating or inhibiting very late activation antigen-4-dependent function.
The mechanisms by which intravenously (IV)-administered hematopoietic cells home to the bone marrow (BM) are poorly defined… 
Highly Cited
1997
Highly Cited
1997
Airway recruitment of leukocytes in mice is dependent on alpha4-integrins and vascular cell adhesion molecule-1.
The involvement of the alpha4-integrin very late activation antigen 4 and vascular cell adhesion molecule-1 (VCAM-1) in leukocyte… 
Highly Cited
1996
Highly Cited
1996
In vitro accommodation of immortalized porcine endothelial cells: resistance to complement mediated lysis and down-regulation of VCAM expression induced by low concentrations of polyclonal human IgG…
The capacity of vascularized xenografts to survive in the face of normal levels of circulating antigraft antibodies and… 
Review
1996
Review
1996
Chemokines active on eosinophils: potential roles in allergic inflammation
p resendy, the eosinophil is recognized as a proinflammatory granulocyte imphcated in protection against parasitic infection and… 
Highly Cited
1995
Highly Cited
1995
Role of the VLA-4 molecule in T cell costimulation. Identification of the tyrosine phosphorylation pattern induced by the ligation of VLA-4.
The very late activated Ag (VLA) molecules not only mediate T cell adhesions, but also provide costimulation in a TCR/CD3… 
Highly Cited
1994
Highly Cited
1994
Arrangement of domains, and amino acid residues required for binding of vascular cell adhesion molecule-1 to its counter-receptor VLA-4 (alpha 4 beta 1)
Interaction of the vascular cell adhesion molecule (VCAM-1) with its counter-receptor very late antigen-4 (VLA-4) (integrin alpha… 
Highly Cited
1993
Highly Cited
1993
HUMAN CD4+ T CELLS PROLIFERATE TO HLA‐DR+ ALLOGENEIC VASCULAR ENDOTHELIUM: IDENTIFICATION OF ACCESSORY INTERACTIONS
Serially passaged human endothelial cell (EC) cultures will stimulate highly purified peripheral blood CD4+ T cells to… 
Highly Cited
1993
Highly Cited
1993
Regulation of human B-cell precursor adhesion to bone marrow stromal cells by cytokines that exert opposing effects on the expression of vascular cell adhesion molecule-1 (VCAM-1).
Self-renewal and differentiation of B-cell precursors is dependent on interactions with bone marrow (BM) stromal cells and… 
Highly Cited
1993
Highly Cited
1993
Migration of natural killer cells across endothelial cell monolayers.
Under certain conditions, NK cells accumulate rapidly at extrahematic sites. In an effort to define the mechanisms underlying… 
Review
1990
Review
1990
Roles of Adhesion Molecules in T‐Cell Recognition: Fundamental Similarities between Four Integrins on Resting Human T Cells (LFA‐1, VLA‐4, VLA‐5, VLA‐6) in Expression, Binding, and Costimulation
This review summarizes our recent work on expression and function of 4 integrins on resting human CD4+ T cells. Three themes are… 
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