Skip to search formSkip to main contentSkip to account menu

Integrin alpha4beta1

Known as: Integrin Alpha4/Beta1, Very Late Antigen-4, alpha4beta1, Integrin 
Integrin alpha4beta1 is a FIBRONECTIN and VCAM-1 receptor present on LYMPHOCYTES; MONOCYTES; EOSINOPHILS; NK CELLS and thymocytes. It is involved in… 
National Institutes of Health

Related topics

Related topics

19 relations

Broader (3)

CD AntigensIntegrinsLymphocyte Homing Receptors
Cell AdhesionCell Adhesion MoleculesCell-Cell Adhesion ProcessCell-Matrix Junction

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2013
Highly Cited
2013
Dual blockade of PD-1 and CTLA-4 combined with tumor vaccine effectively restores T-cell rejection function in tumors.
Tumor progression is facilitated by regulatory T cells (Treg) and restricted by effector T cells. In this study, we document… 
Review
2002
Review
2002
Current understanding of stem cell mobilization: the roles of chemokines, proteolytic enzymes, adhesion molecules, cytokines, and stromal cells.
Highly Cited
1997
Highly Cited
1997
Human cytotrophoblast differentiation/invasion is abnormal in pre-eclampsia.
During human placental development, cytotrophoblast stem cells differentiate and invade the uterus. Simultaneously, the cells… 
Highly Cited
1995
Highly Cited
1995
The integrin VLA-4 supports tethering and rolling in flow on VCAM-1
Selectins have previously been shown to tether a flowing leukocyte to a vessel wall and mediate rolling. Here, we report that an… 
Highly Cited
1993
Highly Cited
1993
Surface expression of alpha 4 integrin by CD4 T cells is required for their entry into brain parenchyma
Cloned CD4 T cell lines that recognize the Ac1-16 peptide of myelin basic protein bound to I-Au were isolated and used to analyze… 
Highly Cited
1991
Highly Cited
1991
Adhesion of human basophils, eosinophils, and neutrophils to interleukin 1-activated human vascular endothelial cells: contributions of endothelial cell adhesion molecules
Cytokines such as interleukin 1 (IL-1) promote adhesiveness in human umbilical vein endothelial cells for leukocytes including… 
Highly Cited
1991
Highly Cited
1991
Evidence for a role of the integrin VLA-4 in lympho-hemopoiesis
Adhesion molecules are probably required for retention of maturing lymphocyte precursors in bone marrow, where they closely… 
Highly Cited
1991
Highly Cited
1991
Fibronectin and VLA-4 in haematopoietic stem cell–microenvironment interactions
THE self-renewal and differentiation of haematopoietic stem cells occurs in vivo and in vitro in direct contact with cells making… 
Highly Cited
1990
Highly Cited
1990
Regulated expression and binding of three VLA (β1) integrin receptors on T cells
REGULATED adhesion of T cells to extracellular matrix (ECM) proteins is likely to be essential in T cell migration. Constitutive… 
Highly Cited
1987
Highly Cited
1987
The VLA protein family. Characterization of five distinct cell surface heterodimers each with a common 130,000 molecular weight beta subunit.
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)