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Integrase

Known as: Integrases, Integrases [Chemical/Ingredient] 
Recombinases that insert exogenous DNA into the host genome. Examples include proteins encoded by the POL GENE of RETROVIRIDAE and also by temperate… 
National Institutes of Health

Related topics

Related topics

21 relations
Anti-HIV AgentsGenes, ViralHIV IntegraseIn Blood

Narrower (5)

Cre recombinaseInTI2 protein, E coliXerC protein, E coliXerD protein, E coli

Broader (2)

DNA NucleotidyltransferasesViral Proteins

Papers overview

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2017
2017
Dolutegravir monotherapy in HIV-infected naive patients with an HIV-RNA load <100 000 copies/mL: a medium-term follow-up
linezolid before introduction of tedizolid. Interestingly, in two cases, though we immediately introduced tedizolid after… 
2013
2013
Isolation and characterisation of bacteriophages infecting environmental strains of Clostridium difficile
Clostridium difficile is a leading cause of nosocomial infections associated with antibiotic treatment. Despite its’ pathogenic… 
2003
2003
Mutations in the C-terminal domain of ALSV (Avian Leukemia and Sarcoma Viruses) integrase alter the concerted DNA integration process in vitro.
Integrase (IN) is the retroviral enzyme responsible for the integration of the DNA copy of the retroviral genome into the host… 
Review
2002
Review
2002
Structure-based inhibitor design targeting HIV-1 integrase.
HIV integrase (IN) is a viral-encoded protein that catalyzes the breaking and joining reactions that mediate integration of viral… 
2002
2002
Mapping the Epitope of an Inhibitory Monoclonal Antibody to the C-terminal DNA-binding Domain of HIV-1 Integrase*
Integrase (IN) catalyzes the insertion of retroviral DNA into chromosomal DNA of a host cell and is one of three virus-encoded… 
2002
2002
Analysis of conserved and non-conserved amino acids critical for ALSV (Avian leukemia and sarcoma viruses) integrase functions in vitro
Summary. Retroviral integrase (IN) is the viral enzyme responsible for the integration of viral DNA into host cellular DNA. In… 
1999
1999
An active foamy virus integrase is required for virus replication.
Foamy viruses (FVs) make use of a replication strategy which is unique among retroviruses and shows analogies to hepadnaviruses… 
1999
1999
Les surprises du décodage de l'information génétique
La conservation du code genetique et de son decryptage par la machinerie traductionnelle est une des universalites du monde… 
Review
1997
Review
1997
Mycobacteriophage D29 contains an integration system similar to that of the temperate mycobacteriophage L5.
A mycobacteriophage D29 DNA fragment cloned in pRM64, a shuttle plasmid that transforms Mycobacterium smegmatis, was sequenced… 
1995
1995
Substrate specificity of Ty1 integrase
Integration of the Saccharomyces cerevisiae retrotransposon Ty1 requires the element-encoded integrase (IN) protein, which is a…