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Integrase

Known as: Integrases, Integrases [Chemical/Ingredient] 
Recombinases that insert exogenous DNA into the host genome. Examples include proteins encoded by the POL GENE of RETROVIRIDAE and also by temperate… 
National Institutes of Health

Related topics

Related topics

21 relations
Anti-HIV AgentsGenes, ViralHIV IntegraseIn Blood

Narrower (5)

Cre recombinaseInTI2 protein, E coliXerC protein, E coliXerD protein, E coli

Broader (2)

DNA NucleotidyltransferasesViral Proteins

Papers overview

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Highly Cited
2006
Highly Cited
2006
Performance of the automated Abbott RealTime HIV-1 assay on a genetically diverse panel of specimens from London: comparison to VERSANT HIV-1 RNA 3.0, AMPLICOR HIV-1 MONITOR v1.5, and LCx HIV RNA…
Highly Cited
2004
Highly Cited
2004
Mechanism of HIV-1 integrase inhibition by styrylquinoline derivatives in vitro.
Styrylquinoline derivatives (SQ) efficiently inhibit the 3'-processing activity of integrase (IN) with IC50 values of between 0.5… 
Highly Cited
2003
Highly Cited
2003
Screening for simian foamy virus infection by using a combined antigen Western blot assay: evidence for a wide distribution among Old World primates and identification of four new divergent viruses.
Highly Cited
2003
Highly Cited
2003
Intracellular transport of human immunodeficiency virus type 1 integrase
The human immunodeficiency virus type 1 integrase protein has karyophilic properties; that is, it localizes to the cell nucleus… 
Highly Cited
1999
Highly Cited
1999
HERV-F (XA34) is a full-length human endogenous retrovirus expressed in placental and fetal tissues.
Highly Cited
1994
Highly Cited
1994
Integrase mutants of human immunodeficiency virus type 1 with a specific defect in integration
A previous genetic analysis of the human immunodeficiency virus type 1 integrase protein failed to identify single amino acid… 
Highly Cited
1993
Highly Cited
1993
Characterization of human immunodeficiency virus type 1 integrase expressed in Escherichia coli and analysis of variants with amino-terminal mutations
Replication of a retroviral genome depends upon integration of the viral DNA into a chromosome of the host cell. The integration… 
Review
1989
Review
1989
A protein binding to the Jk recombination sequence of immunoglobulin genes contains a sequence related to the integrase motif
SITE-SPECIFIC recombination requires conserved DNA sequences specific to each system, and system-specific proteins that recognize… 
Highly Cited
1988
Highly Cited
1988
Micropia: a retrotransposon of Drosophila combining structural features of DNA viruses, retroviruses and non-viral transposable elements.
Highly Cited
1987
Highly Cited
1987
Integration of satellite bacteriophage P4 in Escherichia coli. DNA sequences of the phage and host regions involved in site-specific recombination.
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