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Integrase

Known as: Integrases, Integrases [Chemical/Ingredient] 
Recombinases that insert exogenous DNA into the host genome. Examples include proteins encoded by the POL GENE of RETROVIRIDAE and also by temperate… 
National Institutes of Health

Related topics

Related topics

21 relations
Anti-HIV AgentsGenes, ViralHIV IntegraseIn Blood

Narrower (5)

Cre recombinaseInTI2 protein, E coliXerC protein, E coliXerD protein, E coli

Broader (2)

DNA NucleotidyltransferasesViral Proteins

Papers overview

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2014
2014
The Prediction of Integrase Inhibitors Efficacy in Third Line Regimen afterFirst and Second Line Antiretroviral Therapy Failure in Senegal
The optimal efficacy of the INI depends on the backbone of nucleoside inhibitors, which seems to be challenged in a context of… 
2013
2013
Isolation and characterisation of bacteriophages infecting environmental strains of Clostridium difficile
Clostridium difficile is a leading cause of nosocomial infections associated with antibiotic treatment. Despite its’ pathogenic… 
2013
2013
Identification of novel inhibitors of HIV-1 integrase using pharmacophore-based virtual screening combined with molecular docking strategies
Human immunodeficiency virus type-1 (HIV-1) integrase is one of three enzymes encoded by the HIV genome for effective viral… 
2010
2010
Active site binding interactions of β-carboline derivative for HIV reverse transcriptase, protease and integrase
Recently Anti-HIV activity of β-carboline derivatives is reported. The highly active compound 1-Formyl-beta-carboline-3… 
2007
2007
[HIV-1 integrase inhibition by modified oligonucleotides: optimization of the inhibitor structure].
Integration of human immunodeficiency virus type 1 DNA into the infected cell genome is one of the key steps of the viral… 
Review
2002
Review
2002
Structure-based inhibitor design targeting HIV-1 integrase.
HIV integrase (IN) is a viral-encoded protein that catalyzes the breaking and joining reactions that mediate integration of viral… 
2002
2002
Mapping the Epitope of an Inhibitory Monoclonal Antibody to the C-terminal DNA-binding Domain of HIV-1 Integrase*
Integrase (IN) catalyzes the insertion of retroviral DNA into chromosomal DNA of a host cell and is one of three virus-encoded… 
1999
1999
An active foamy virus integrase is required for virus replication.
Foamy viruses (FVs) make use of a replication strategy which is unique among retroviruses and shows analogies to hepadnaviruses… 
1999
1999
Les surprises du décodage de l'information génétique
La conservation du code genetique et de son decryptage par la machinerie traductionnelle est une des universalites du monde… 
Review
1997
Review
1997
Mycobacteriophage D29 contains an integration system similar to that of the temperate mycobacteriophage L5.
A mycobacteriophage D29 DNA fragment cloned in pRM64, a shuttle plasmid that transforms Mycobacterium smegmatis, was sequenced…