HIV Integrase

Known as: HIV Integration Protein, Integration Protein, HIV, HIV Integrase [Chemical/Ingredient] 
Enzyme of the HUMAN IMMUNODEFICIENCY VIRUS that is required to integrate viral DNA into cellular DNA in the nucleus of a host cell. HIV integrase is… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

2006-2017
02420062017

Papers overview

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2016
2016
New genetic tools are needed to understand the functional interactions between HIV and human host factors in primary cells. We… (More)
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2013
2013
Celiac Disease (CD) is a chronic inflammatory enteropathy, triggered in genetically susceptible individuals by dietary gluten… (More)
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2013
2013
Protein-DNA interactions are essential for many biological processes. X-ray crystallography can provide high-resolution… (More)
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2012
2012
Targeting the HIV integrase (HIV IN) is a clinically validated approach for designing novel anti-HIV therapies. We have… (More)
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2011
2011
Identification of cytotoxic T lymphocyte (CTL) epitopes from tumor antigens is essential for the development of peptide vaccines… (More)
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2010
2010
Integrase plays a critical role in the recombination of viral DNA into the host genome. Therefore, over the past decade, it has… (More)
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2008
2008
Small-molecule inhibitors of HIV integrase (HIV IN) have emerged as a promising new class of antivirals for the treatment of HIV… (More)
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2008
2008
A series of novel isatine-sulphonamide derivatives have been synthesized by combining isatin derivatives with sulphonamides. The… (More)
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2007
2007
The two-metal binding model we previously reported as an inhibition mechanism of HIV integrase (HIV IN) produced a new direction… (More)
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2006
2006
We propose a two-metal binding model as a potential mechanism of chelating inhibitors against HIV integrase (HIV IN) represented… (More)
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