Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

Inositol 1,4,5-Trisphosphate

Known as: 1,4,5-IP3, INs-P3, Myo-Inositol 1,4,5-Trisphosphate 
Intracellular messenger formed by the action of phospholipase C on phosphatidylinositol 4,5-bisphosphate, which is one of the phospholipids that make… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2007
Review
2007
The inositol 1,4,5-trisphosphate (InsP3) receptors (InsP3Rs) are a family of Ca2+ release channels localized predominately in the… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Review
1993
Review
1993
At fertilization mammalian eggs exhibit repetitive rises in the cytoplasmic Ca2+ concentration (Ca2+ oscillations), associated… Expand
Highly Cited
1992
Highly Cited
1992
The range of messenger action of a point source of Ca2+ or inositol 1,4,5-trisphosphate (IP3) was determined from measurements of… Expand
Highly Cited
1992
Highly Cited
1992
Relying on quantitative measurements of Ca2+ activation and inhibition of the inositol 1,4,5-trisphosphate (IP3) receptor in the… Expand
Highly Cited
1991
Highly Cited
1991
Inositol 1,4,5-trisphosphate (IP3)-induced calcium release from intracellular stores is a regulator of cytosolic-free calcium… Expand
Highly Cited
1990
Highly Cited
1990
  • M. Iino
  • The Journal of general physiology
  • 1990
  • Corpus ID: 18382727
Ca2+ dependence of the inositol 1,4,5-trisphosphate (IP3)-induced Ca release was studied in saponin-skinned smooth muscle fiber… Expand
  • table I
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Review
1989
Review
1989
Inositol 1,4,5-trisphosphate is a second messenger which regulates intracellular calcium both by mobilizing calcium from internal… Expand
Highly Cited
1989
Highly Cited
1989
Cloning and expression of functional P400 protein from cerebellar Purkinje neurons shows that this protein is a receptor for… Expand
Highly Cited
1989
Highly Cited
1989
Hepatocytes are well coupled by gap junctions, which allow the diffusion of small molecules between cells. Although gap junctions… Expand
  • figure 1
  • figure 2
  • figure 3
Highly Cited
1983
Highly Cited
1983
Activation of receptors for a wide variety of hormones and neurotransmitters leads to an increase in the intracellular level of… Expand