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Indobufen, (S)-

 
National Institutes of Health

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2018
2018
Indobufen is a new generation of anti-platelet aggregation drug, but studies were not sufficient on its anticoagulant effects. In… Expand
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2018
2018
Indobufen (Ibustrin®), a reversible inhibitor of platelet aggregation, exists in two enantiomeric forms in 1:1 ratio. Here, we… Expand
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2015
2015
Airway epithelial NF-κB activation is observed in asthmatic subjects and is a cause of airway inflammation in mouse models of… Expand
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2009
2009
Hippocampal area CA3 is critically involved in the formation of nonoverlapping neuronal subpopulations (“pattern separation”) to… Expand
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2007
2007
Metabotropic glutamate receptors (mGluRs) modulate neural excitability and network tone in many brain regions. Expression of… Expand
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1997
1997
Serotonin (5-HT) applied at 1, 3, and 10 microM into the striatum of halothane-anesthetized rats by in vivo microdialysis… Expand
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1993
1993
The excretion balance and urinary metabolites of the S-enantiomer of indobufen, ((S)2-[p-(1-oxo-2-isoindolinyl)-phenyl]butyric… Expand
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1992
1992
The plasma pharmacokinetics and urinary elimination of the enantiomers of indobufen (2-[p-(1-oxo-2-isoindolinyl)-phenyl]butyric… Expand
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1990
1990
Racemic indobufen inhibits human platelet aggregation by reducing thromboxane (TX) A2 biosynthesis. In order to ascertain which… Expand
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1990
1990
In clinical trials carried out to assess the efficacy of different drugs in reducing the frequency of occlusion after coronary… Expand
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