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Indobufen, (S)-

National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Prediction of the human in vivo antiplatelet effect of S- and R-indobufen using population pharmacodynamic modeling and simulation based on in vitro platelet aggregation test
Indobufen (Ibustrin®), a reversible inhibitor of platelet aggregation, exists in two enantiomeric forms in 1:1 ratio. Here, we… 
2009
2009
Molecular Bidirectional Hebbian Plasticity at Hippocampal Mossy Fiber Synapses on CA 3 Interneurons
Hippocampal area CA3 is critically involved in the formation of nonoverlapping neuronal subpopulations (“pattern separation”) to… 
2000
2000
Stereoselectivity at the beta2-adrenoceptor on macrophages is a major determinant of the anti-inflammatory effects of beta2-agonists.
Previous research has shown that beta-adrenoceptor (beta-AR) agonists have potent anti-inflammatory capabilities, e.g… 
Highly Cited
1997
Highly Cited
1997
Serotonin Stimulation of 5‐HT4 Receptors Indirectly Enhances In Vivo Dopamine Release in the Rat Striatum
Abstract: Serotonin (5‐HT) applied at 1, 3, and 10 µM into the striatum of halothane‐anesthetized rats by in vivo microdialysis… 
Highly Cited
1994
Highly Cited
1994
An enantiomer-enantiomer interaction of (S)- and (R)-propafenone modifies the effect of racemic drug therapy.
BACKGROUND Therapy with racemic compounds produces effects that can be attributed to both (S)- and (R)-enantiomers. Here we have… 
1993
1993
Excretion balance and urinary metabolites of the S-enantiomer of indobufen in rats and mice.
1992
1992
The dispositional enantioselectivity of indobufen in man.
1990
1990
Effects of racemic, S- and R-indobufen on cyclooxygenase and lipoxygenase activities in human whole blood.
1990
1990
A linear model suitable for assessing graft patency in controlled clinical trials. SINBA Group.
1990
1990
The dispositional enantioselectivity of indobufen in rat and mouse.
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