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Inamrinone

Known as: Amrinona, Amrinone, Amrinonum 
A synthetic bipyridine phosphodiesterase inhibitor with inotropic and vasodilator properties. Inamrinone inhibits type III phosphodiesterase, which… Expand
National Institutes of Health

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Highly Cited
2000
Highly Cited
2000
The inhibitory potential of novel anti-platelet aggregatory cilostamide analogues on phosphodiesterase (PDE) isozyme activities… Expand
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Highly Cited
1997
Highly Cited
1997
Injury of the arterial wall induces the formation of the neoin-tima1. This structure is generated by the growth of mitogenically… Expand
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Highly Cited
1996
Highly Cited
1996
The use of bone marrow transplantation to treat malignant and nonmalignant disease is growing. In 1990, more than 10 000 bone… Expand
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Highly Cited
1995
Highly Cited
1995
Chloride channel activity of cystic fibrosis transmembrane conductance regulator (CFTR) requires activation of protein kinase A… Expand
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Highly Cited
1987
Highly Cited
1987
Ventricular muscle contains a low Km, cyclic AMP-specific form of phosphodiesterase (PDE III), which is believed to represent the… Expand
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Highly Cited
1986
Highly Cited
1986
We have identified and highly purified a "low Km" cAMP phosphodiesterase from bovine cardiac muscle. This phosphodiesterase was… Expand
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Highly Cited
1984
Highly Cited
1984
To determine the hemodynamic and clinical effects of long-term positive inotropic stimulation on the myocardium, we treated 31… Expand
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Highly Cited
1983
Highly Cited
1983
Milrinone, a derivative of amrinone, has nearly 20 times the inotropic potency of the parent compound and does not cause fever or… Expand
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Highly Cited
1979
Highly Cited
1979
The cardiotonic activity of a new, noncatechol, nonglycoside agent, amrinone, waa investigated in vitro and in anesthestized and… Expand
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Highly Cited
1978
Highly Cited
1978
Amrinone, a new bipyridine derivative, exerts a positive inotropic action in experimental preparations and is effective when… Expand
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