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Inamrinone

Known as: Amrinona, Amrinone, Amrinonum 
A synthetic bipyridine phosphodiesterase inhibitor with inotropic and vasodilator properties. Inamrinone inhibits type III phosphodiesterase, which… 
National Institutes of Health

Related topics

Related topics

29 relations
100 ML Milrinone Lactate 0.2 MG/ML InjectionAortic Valve InsufficiencyCardiomyopathy, DilatedCongestive heart failure

Narrower (6)

AmcoralCordemcuraInocorN-acetylamrinone

Broader (4)

Calcium Channel BlockersCardiotonic AgentsPhosphodiesterase 3 InhibitorsVasodilator Agents

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
1995
Highly Cited
1995
CFTR-mediated chloride permeability is regulated by type III phosphodiesterases in airway epithelial cells.
Chloride channel activity of cystic fibrosis transmembrane conductance regulator (CFTR) requires activation of protein kinase A… 
Highly Cited
1993
Highly Cited
1993
Use of amrinone and glucagon in a case of calcium channel blocker overdose.
Review
1989
Review
1989
Biochemical aspects of inhibition of cardiovascular low (Km) cyclic adenosine monophosphate phosphodiesterase.
Highly Cited
1988
Highly Cited
1988
Do positive inotropic agents adversely affect the survival of patients with chronic congestive heart failure? I. Introduction.
Highly Cited
1986
Highly Cited
1986
Pharmacology of the bipyridines: amrinone and milrinone.
: The cardiovascular bipyridines amrinone and milrinone are positive inotropic agents with vasodilator properties. When their… 
Highly Cited
1984
Highly Cited
1984
Inotropic and vasodilator effects of amrinone on isolated human tissue.
The effects of amrinone on human umbilical artery and human myocardium were studied. Amrinone produced dose related increases in… 
Highly Cited
1984
Highly Cited
1984
Comparison of the effects of amrinone and sodium nitroprusside on haemodynamics, contractility, and myocardial metabolism in patients with cardiac failure due to coronary artery disease and dilated…
The effects of intravenous amrinone and sodium nitroprusside on haemodynamic indices, left ventricular contractility, and… 
Highly Cited
1983
Highly Cited
1983
Long-term therapy with a new cardiotonic agent, WIN 47203: drug-dependent improvement in cardiac performance and progression of the underlying disease.
Highly Cited
1983
Highly Cited
1983
Side effects of amrinone therapy.
We gave intravenous amrinone to 40 patients in heart failure, and oral amrinone to 18 patients. Acute intravenous administration… 
Highly Cited
1981
Highly Cited
1981
Relationship between amrinone plasma concentration and cardiac index
Amrinone was given to 14 patients with congestive heart failure as an intravenous bolus (1 mg/sec) at doses ranging from 0.5 to 3… 
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