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Dilated cardiomyopathy and hypertrophic cardiomyopathy arise from mutations in many genes. TTN, the gene encoding the… Expand OBJECTIVES
We studied the prognostic implications of midwall fibrosis in dilated cardiomyopathy (DCM) in a prospective… Expand BACKGROUND
Patients with nonischemic dilated cardiomyopathy are at substantial risk for sudden death from cardiac causes. However… Expand Amplification of the gene encoding the ErbB2 (Her2/neu) receptor tyrosine kinase is critical for the progression of several forms… Expand Dilated cardiomyopathy is a severe pathology of the heart with poorly understood etiology. Disruption of the gene encoding the… Expand BACKGROUND
Inherited mutations cause approximately 35 percent of cases of dilated cardiomyopathy; however, few genes associated… Expand The Sod2 gene for Mn–superoxide dismutase (MnSOD), an intramitochondrial free radical scavenging enzyme that is the first line of… Expand BACKGROUND
Because systolic and diastolic dysfunction frequently coexist, it is hypothesized that a combined measure of left… Expand Idiopathic dilated cardiomyopathy (IDC) is a primary myocardial disease of unknown cause characterized by left ventricular or… Expand Several small studies have suggested beneficial effects of long-term beta-blocker treatment in idiopathic dilated cardiomyopathy… Expand