Impromidine

Known as: Guanidine, N-(3-(1H-imidazol-4-yl)propyl)-N'-(2-(((5-methyl-1H-imidazol-4-yl)methyl)thio)ethyl)-, Impromidine [Chemical/Ingredient] 
A highly potent and specific histamine H2 receptor agonist. It has been used diagnostically as a gastric secretion indicator.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1978-2010
010203019782010

Papers overview

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2011
2011
Histamine H(3) and H(4) receptors are highly related G protein-coupled receptors. Preclinical and clinical data strongly suggest… (More)
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Highly Cited
1996
Highly Cited
1996
We have demonstrated previously the importance of histaminergic neurons in arousal mechanisms. In addition to their ascending… (More)
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Highly Cited
1992
Highly Cited
1992
1. The effect of agents which interact with the histamine H3 receptor on potassium-stimulated tritium release from slices of rat… (More)
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1990
1990
Human neutrophils possess an NADPH oxidase which catalyzes superoxide (O inf2 sup− ) formation and is activated by chemotactic… (More)
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Highly Cited
1989
Highly Cited
1989
The effects of histamine and related drugs on the evoked tritium overflow from superfused rat brain cortex slices preincubated… (More)
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Highly Cited
1988
Highly Cited
1988
Rat brain cortex slices preincubated with 3H-serotonin were superfused with physiological salt solution (containing citalopram… (More)
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1985
1985
The actions of betahistine (N alpha-methyl-2-pyridylethylamine) on brain histamine receptors were investigated in a series of… (More)
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1985
1985
Impromidine (1) is a potent and selective histamine H2 receptor agonist and its structure comprises a strongly basic guanidine… (More)
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1981
1981
The present study chartacterizes myocardial effects of two new histaminergic H2-receptor specific compounds, impromidine, and… (More)
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1978
1978
PREVIOUSLY described selective agonists for histamine H2 receptors are 4-methylhistamine1, related congeners2–6 and dimaprit7… (More)
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