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Impromidine

Known as: Guanidine, N-(3-(1H-imidazol-4-yl)propyl)-N'-(2-(((5-methyl-1H-imidazol-4-yl)methyl)thio)ethyl)-, Impromidine [Chemical/Ingredient] 
A highly potent and specific histamine H2 receptor agonist. It has been used diagnostically as a gastric secretion indicator.
National Institutes of Health

Related topics

Related topics

8 relations

Broader (1)

Histamine Agonists
In Bloodagonistsanalogs & derivativesantagonists & inhibitors

Papers overview

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Highly Cited
2011
Highly Cited
2011
Receptor-specific functional efficacies of alkyl imidazoles as dual histamine H3/H4 receptor ligands.
Highly Cited
2002
Highly Cited
2002
Mouse light/dark box test reveals anxiogenic-like effects by activation of histamine H1 receptors
1998
1998
Histamine increases the bursting activity of pyramidal cells in the CA3 region of mouse hippocampus
1992
1992
Stimulation of acid secretion increases the gastric gland luminal pressure in the rat.
Highly Cited
1990
Highly Cited
1990
Histamine depolarizes rat medial vestibular nucleus neurons recorded intracellularly in vitro
1989
1989
Studies on the cardiovascular actions of central histamine H1 and H2 receptors.
Highly Cited
1988
Highly Cited
1988
A highly potent and selective H3 agonist relaxes rabbit middle cerebral artery, in vitro.
1987
1987
Comparison of the effects of histamine H1- and H2-receptor agonists on large and small airways in normal and asthmatic subjects.
1982
1982
Histamine-induced rise in core temperature of chloral-anaesthetized rats: Mediation by H2-receptors located in the preopticus area of hypothalamus
Highly Cited
1978
Highly Cited
1978
Impromidine (SK&F 92676) is a very potent and specific agonist for histamine H2 receptors
PREVIOUSLY described selective agonists for histamine H2 receptors are 4-methylhistamine1, related congeners2–6 and dimaprit7… 
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