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Impromidine

Known as: Guanidine, N-(3-(1H-imidazol-4-yl)propyl)-N'-(2-(((5-methyl-1H-imidazol-4-yl)methyl)thio)ethyl)-, Impromidine [Chemical/Ingredient] 
A highly potent and specific histamine H2 receptor agonist. It has been used diagnostically as a gastric secretion indicator.
National Institutes of Health

Related topics

Related topics

8 relations

Broader (1)

Histamine Agonists
In Bloodagonistsanalogs & derivativesantagonists & inhibitors

Papers overview

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Review
2000
Review
2000
Selective ligands as tools to study histamine receptors.
Highly Cited
1997
Highly Cited
1997
Long-term increase of hippocampal excitability by histamine and cyclic AMP
Highly Cited
1995
Highly Cited
1995
Cholinergic nucleus basalis neurons are excited by histamine in vitro
1990
1990
Inhibition of electrically evoked contractions of guinea-pig ileum preparations mediated by the histamine H3 receptor.
Highly Cited
1987
Highly Cited
1987
Autoinhibition of histamine synthesis mediated by presynaptic H3-receptors
Highly Cited
1985
Highly Cited
1985
Autoregulation of histamine release in brain by presynaptic H3-receptors
Highly Cited
1985
Highly Cited
1985
Actions of betahistine at histamine receptors in the brain.
Highly Cited
1985
Highly Cited
1985
Evidence for excitatory actions of histamine on supraoptic neurons in vitro: Mediation by an H1-type receptor
Highly Cited
1984
Highly Cited
1984
Evidence for the existence of histamine H1- and H2-receptors on astrocytes of cultured rat central nervous system
Highly Cited
1978
Highly Cited
1978
Impromidine (SK&F 92676) is a very potent and specific agonist for histamine H2 receptors
PREVIOUSLY described selective agonists for histamine H2 receptors are 4-methylhistamine1, related congeners2–6 and dimaprit7… 
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