Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

Impromidine

Known as: Guanidine, N-(3-(1H-imidazol-4-yl)propyl)-N'-(2-(((5-methyl-1H-imidazol-4-yl)methyl)thio)ethyl)-, Impromidine [Chemical/Ingredient] 
A highly potent and specific histamine H2 receptor agonist. It has been used diagnostically as a gastric secretion indicator.
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2011
Highly Cited
2011
Histamine H(3) and H(4) receptors are highly related G protein-coupled receptors. Preclinical and clinical data strongly suggest… Expand
  • figure 1
  • table 1
  • table 2
  • table 3
  • table 4
Highly Cited
1996
Highly Cited
1996
We have demonstrated previously the importance of histaminergic neurons in arousal mechanisms. In addition to their ascending… Expand
  • figure 1
  • figure 3
  • figure 4
  • figure 5
  • figure 6
Highly Cited
1994
Highly Cited
1994
Cats were chronically implanted with electrodes for polygraphic recordings and cannulae for intracerebral microinjections in… Expand
Highly Cited
1992
Highly Cited
1992
1 The effect of agents which interact with the histamine H3 receptor on potassium‐stimulated tritium release from slices of rat… Expand
Highly Cited
1990
Highly Cited
1990
The H3-histamine receptor provides feedback inhibition of histamine synthesis and release as well as inhibition of other… Expand
Highly Cited
1987
Highly Cited
1987
The regulation of histamine synthesis was studied on rat brain slices or synaptosomes labeled with L-[3H]histidine… Expand
Highly Cited
1985
Highly Cited
1985
Regulation of histamine release was studied mainly on brain slices prelabeled with L-[3H]-histidine and depolarized by increased… Expand
Highly Cited
1985
Highly Cited
1985
The actions of betahistine (N alpha-methyl-2-pyridylethylamine) on brain histamine receptors were investigated in a series of… Expand
1985
1985
Impromidine (1) is a potent and selective histamine H2 receptor agonist and its structure comprises a strongly basic guanidine… Expand
Highly Cited
1978
Highly Cited
1978
PREVIOUSLY described selective agonists for histamine H2 receptors are 4-methylhistamine1, related congeners2–6 and dimaprit7… Expand