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Impromidine

Known as: Guanidine, N-(3-(1H-imidazol-4-yl)propyl)-N'-(2-(((5-methyl-1H-imidazol-4-yl)methyl)thio)ethyl)-, Impromidine [Chemical/Ingredient] 
A highly potent and specific histamine H2 receptor agonist. It has been used diagnostically as a gastric secretion indicator.
National Institutes of Health

Papers overview

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2011
2011
Histamine H(3) and H(4) receptors are highly related G protein-coupled receptors. Preclinical and clinical data strongly suggest… Expand
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Highly Cited
2004
Highly Cited
2004
SummaryThe effects of histamine and related drugs on the evoked tritium overflow from superfused rat brain cortex slices… Expand
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Highly Cited
2004
Highly Cited
2004
SummaryRat brain cortex slices preincubated with 3H-serotonin were superfused with physiological salt solution (containing… Expand
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Highly Cited
1998
Highly Cited
1998
1. The main objective of this study was to analyse the role and mode of action of the mast cell mediator histamine in leukocyte… Expand
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Highly Cited
1996
Highly Cited
1996
We have demonstrated previously the importance of histaminergic neurons in arousal mechanisms. In addition to their ascending… Expand
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Highly Cited
1992
Highly Cited
1992
1. The effect of agents which interact with the histamine H3 receptor on potassium-stimulated tritium release from slices of rat… Expand
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Highly Cited
1987
Highly Cited
1987
The regulation of histamine synthesis was studied on rat brain slices or synaptosomes labeled with L-[3H]histidine… Expand
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Highly Cited
1985
Highly Cited
1985
The actions of betahistine (N alpha-methyl-2-pyridylethylamine) on brain histamine receptors were investigated in a series of… Expand
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Highly Cited
1985
Highly Cited
1985
Regulation of histamine release was studied mainly on brain slices prelabeled with L-[3H]-histidine and depolarized by increased… Expand
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1978
1978
PREVIOUSLY described selective agonists for histamine H2 receptors are 4-methylhistamine1, related congeners2–6 and dimaprit7… Expand
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