Immunoglobulin Isotypes

Known as: Immunoglobulin Isotype, Antibody Isotype, Immunoglobulin Classes 
The classes of immunoglobulins found in any species of animal. In man there are nine classes that migrate in five different groups in electrophoresis… (More)
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
Teleost fish are the most primitive bony vertebrates that contain immunoglobulins. In contrast to mammals and birds, these… (More)
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Highly Cited
2002
Highly Cited
2002
BACKGROUND We have previously proposed that deamination of cytosine to uracil at sites within the immunoglobulin loci by… (More)
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Highly Cited
1998
Highly Cited
1998
Isotype switching is the DNA recombination mechanism by which antibody genes diversify immunoglobulin effector functions. In… (More)
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Review
1998
Review
1998
Members of the mammalian protein kinase C (PKC) superfamily play key regulatory roles in a multitude of cellular processes… (More)
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Highly Cited
1993
Highly Cited
1993
We have employed a method based on the Cre-loxP recombination system of bacteriophage P1 to generate a mouse strain in which the… (More)
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Review
1990
Review
1990
Several specific conclusions can be drawn from these studies: 1. IL-4 is required for the generation of both primary polyclonal… (More)
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Highly Cited
1988
Highly Cited
1988
The regulation of the subclass of immunoglobulin secreted by B cells has been studied in vitro in polyclonal systems using… (More)
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Highly Cited
1987
Highly Cited
1987
Gamma interferon (IFN-gamma) and B cell stimulatory factor-1 (BSF-1), also known as interleukin-4, are T cell-derived lymphokines… (More)
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Highly Cited
1986
Highly Cited
1986
Almost all B cells in autoimmune mice with the viable motheaten (mev) mutation express the Ly-1 cell surface antigen, which marks… (More)
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Highly Cited
1979
Highly Cited
1979
We have isolated a subclone of the mouse myeloma cell line P3-X63-Ag8 that does not express immunoglobulin heavy or light chains… (More)
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