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Imipramine Hydrochloride
Known as:
Imipramine Hydrochloride [Chemical/Ingredient]
, Imipramine Monohydrochloride
, imipramine hcl
The hydrochloride salt form of imipramine, a synthetic tricyclic derivative, antidepressant Imipramine enhances monoamine neurotransmission in…
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National Institutes of Health
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Related topics
Related topics
18 relations
Affective Disorders, Psychotic
Antidepressive Agents
Attention deficit hyperactivity disorder
CYP1A2 protein, human
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Narrower (1)
Tofranil
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
1993
Highly Cited
1993
Antidepressants for the treatment of generalized anxiety disorder. A placebo-controlled comparison of imipramine, trazodone, and diazepam.
K. Rickels
,
R. Downing
,
E. Schweizer
,
H. Hassman
Archives of general psychiatry
1993
Corpus ID: 32619944
OBJECTIVE The current study examines whether antidepressants, contrary to current thinking, are safe and effective treatments for…
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Highly Cited
1992
Highly Cited
1992
Five-year outcome for maintenance therapies in recurrent depression.
D. Kupfer
,
E. Frank
,
+5 authors
V. Grochocinski
Archives of general psychiatry
1992
Corpus ID: 42009371
After conducting a randomized, 3-year maintenance trial in 128 patients with recurrent depression who had responded to combined…
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Highly Cited
1989
Highly Cited
1989
National Institute of Mental Health Treatment of Depression Collaborative Research Program. General effectiveness of treatments.
I. Elkin
,
M. Shea
,
+7 authors
J. Docherty
Archives of general psychiatry
1989
Corpus ID: 30715468
We investigated the effectiveness of two brief psychotherapies, interpersonal psychotherapy and cognitive behavior therapy, for…
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Highly Cited
1987
Highly Cited
1987
Imipramine in prepubertal major depressive disorders.
J. Puig-Antich
,
J. Perel
,
+6 authors
R. Stiller
Archives of general psychiatry
1987
Corpus ID: 20725725
The potential effectiveness of imipramine hydrochloride (up to 5 mg/kg/d) was investigated in 53 prepubertal children suffering…
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Highly Cited
1984
Highly Cited
1984
Drug therapy in the prevention of recurrences in unipolar and bipolar affective disorders. Report of the NIMH Collaborative Study Group comparing lithium carbonate, imipramine, and a lithium…
R. Prien
,
D. Kupfer
,
+4 authors
W. E. Johnson
Archives of general psychiatry
1984
Corpus ID: 19542192
In a double-blind, long-term follow-up study, 117 bipolar patients received lithium carbonate, imipramine hydrochloride, or both…
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Highly Cited
1983
Highly Cited
1983
Treatment of phobias. I. Comparison of imipramine hydrochloride and placebo.
C. Zitrin
,
D. Klein
,
M. Woerner
,
D. Ross
Archives of general psychiatry
1983
Corpus ID: 8340344
In a controlled-outcome study of phobias, 218 adult phobic patients (147 women and 71 men) received a course of 26 weekly…
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Highly Cited
1980
Highly Cited
1980
Treatment of endogenous anxiety with phobic, hysterical, and hypochondriacal symptoms.
D. Sheehan
,
J. Ballenger
,
G. Jacobsen
Archives of general psychiatry
1980
Corpus ID: 25244467
Endogenous anxiety (anxiety hysteria, agoraphobia with panic attacks) is characterized by sudden, spontaneous panic attacks…
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Highly Cited
1977
Highly Cited
1977
Clinical implications of imipramine plasma levels for depressive illness.
A. Glassman
,
J. Perel
,
M. Shostak
,
S. Kantor
,
J. Fleiss
Archives of general psychiatry
1977
Corpus ID: 44731471
Sixty depressed nonschizophrenic patients were admitted to a research unit. Following one drug-free week and one week of placebo…
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Highly Cited
1977
Highly Cited
1977
Cardiac antiarrhythmic effect of imipramine hydrochloride.
J. Bigger
,
E. Giardina
,
J. Perel
,
S. Kantor
,
A. Glassman
The New England journal of medicine
1977
Corpus ID: 45946330
Over 20 million prescriptions are written annually for tricyclic antidepressants.1 The cardiotoxicity of overdosage is well…
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Highly Cited
1958
Highly Cited
1958
The treatment of depressive states with G 22355 (imipramine hydrochloride).
R. Kuhn
The American journal of psychiatry
1958
Corpus ID: 37484672
Over a three-year period, more than 500 psychiatric patients of various diagnostic categories were treated with imipramine…
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