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Imipramine Hydrochloride

Known as: Imipramine Hydrochloride [Chemical/Ingredient], Imipramine Monohydrochloride, imipramine hcl 
The hydrochloride salt form of imipramine, a synthetic tricyclic derivative, antidepressant Imipramine enhances monoamine neurotransmission in… 
National Institutes of Health

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Affective Disorders, PsychoticAntidepressive AgentsAttention deficit hyperactivity disorderCYP1A2 protein, human

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Highly Cited
1993
Highly Cited
1993
Antidepressants for the treatment of generalized anxiety disorder. A placebo-controlled comparison of imipramine, trazodone, and diazepam.
OBJECTIVE The current study examines whether antidepressants, contrary to current thinking, are safe and effective treatments for… 
Highly Cited
1992
Highly Cited
1992
Five-year outcome for maintenance therapies in recurrent depression.
After conducting a randomized, 3-year maintenance trial in 128 patients with recurrent depression who had responded to combined… 
Highly Cited
1989
Highly Cited
1989
National Institute of Mental Health Treatment of Depression Collaborative Research Program. General effectiveness of treatments.
We investigated the effectiveness of two brief psychotherapies, interpersonal psychotherapy and cognitive behavior therapy, for… 
Highly Cited
1987
Highly Cited
1987
Imipramine in prepubertal major depressive disorders.
The potential effectiveness of imipramine hydrochloride (up to 5 mg/kg/d) was investigated in 53 prepubertal children suffering… 
Highly Cited
1984
Highly Cited
1984
Drug therapy in the prevention of recurrences in unipolar and bipolar affective disorders. Report of the NIMH Collaborative Study Group comparing lithium carbonate, imipramine, and a lithium…
In a double-blind, long-term follow-up study, 117 bipolar patients received lithium carbonate, imipramine hydrochloride, or both… 
Highly Cited
1983
Highly Cited
1983
Treatment of phobias. I. Comparison of imipramine hydrochloride and placebo.
In a controlled-outcome study of phobias, 218 adult phobic patients (147 women and 71 men) received a course of 26 weekly… 
Highly Cited
1980
Highly Cited
1980
Treatment of endogenous anxiety with phobic, hysterical, and hypochondriacal symptoms.
Endogenous anxiety (anxiety hysteria, agoraphobia with panic attacks) is characterized by sudden, spontaneous panic attacks… 
Highly Cited
1977
Highly Cited
1977
Clinical implications of imipramine plasma levels for depressive illness.
Sixty depressed nonschizophrenic patients were admitted to a research unit. Following one drug-free week and one week of placebo… 
Highly Cited
1977
Highly Cited
1977
Cardiac antiarrhythmic effect of imipramine hydrochloride.
Over 20 million prescriptions are written annually for tricyclic antidepressants.1 The cardiotoxicity of overdosage is well… 
Highly Cited
1958
Highly Cited
1958
The treatment of depressive states with G 22355 (imipramine hydrochloride).
  • R. Kuhn
  • The American journal of psychiatry
  • 1958
  • Corpus ID: 37484672
Over a three-year period, more than 500 psychiatric patients of various diagnostic categories were treated with imipramine… 
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