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Imetelstat
Known as:
DNA, d(3'-amino-3'-deoxy-P-thio)(T-A-G-G-G-T-T-A-G-A-C-A-A), 5'-[O-[2-hydroxy-3- [(1-oxohexadecyl)amino]propyl] hydrogen phosphorothioate]
A synthetic lipid-conjugated, 13-mer oligonucleotide N3'-P5'-thio-phosphoramidate with potential antineoplastic activity. Complementary to the…
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National Institutes of Health
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Related topics
Related topics
8 relations
Narrower (3)
AMG 706
motesanib
motesanib diphosphate
Imetelstat Sodium
NCIt Antineoplastic Agent Terminology
analogs & derivatives
Broader (2)
Indoles
Niacinamide
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
PS1456 FAVORABLE OVERALL SURVIVAL OF IMETELSTAT-TREATED RELAPSED/REFRACTORY MYELOFIBROSIS PATIENTS COMPARED WITH CLOSELY MATCHED REAL WORLD DATA
A. Kuykendall
,
Y. Wan
,
+9 authors
R. Komrokji
HemaSphere
2019
Corpus ID: 196535998
• Myelofibrosis (MF), parꢀcularly Intermediate-2 (Int-2) or High-Risk disease per Dynamic Internaꢀonal Prognosꢀc Scoring System…
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2015
2015
Imetelstat : un inhibiteur de télomérase prometteur dans la thrombocythémie essentielle
J. Paillassa
2015
Corpus ID: 98112544
Les therapies actuellement utilisees dans les thrombocythemies essentielles de haut risque ne font que reduire la numeration…
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2013
2013
Preclinical Studies of Telomerase Inhibitor Imetelstat in Non-small Cell Lung Cancer
Robin E. Frink
2013
Corpus ID: 74380026
2011
2011
The effect of the telomerase antagonist Imetelstat in esophageal carcinoma
Xuping Wu
,
Shirin Smavadati
,
+7 authors
Y. Paulsson-Karlsson
2011
Corpus ID: 82231460
Oesophageal cancer is a malignant and aggressive disease with very poor survival. The aim of this thesis was to evaluate novel…
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2010
2010
Cancer esearch or and Stem Cell Biology Telomerase Inhibitor Imetelstat Depletes Cancer Stem R ls in Breast and Pancreatic Cancer Cell Lines
N. Joseph
,
R. Tressler
,
+6 authors
N. Go
2010
Corpus ID: 20543539
Downlo cer stem cells (CSC) are rare drug-resistant cancer cell subsets proposed to be responsible for the enance and recurrence…
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2010
2010
Can be Safely Targeted for Telomerase Inhibition Neural Tumor-Initiating Cells Have Distinct Telomere Maintenance
P. Castelo-Branco
,
Cindy H. Zhang
,
+10 authors
U. Tabori
2010
Corpus ID: 18849630
Purpose: Cancer recurrence is one of the major setbacks in oncology. Maintaining telomeres is essential for sustaining the…
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2010
2010
Cells in Breast and Pancreatic Cancer Cell Lines The Telomerase Inhibitor Imetelstat Depletes Cancer Stem
R. Tressler
,
Ekaterina Bassett
,
+5 authors
N. Go
2010
Corpus ID: 207910674
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