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AMG 706

Known as: AMG-706, AMG706 
An orally bioavailable multiple-receptor tyrosine kinase inhibitor with potential antineoplastic activity. AMG 706 selectively targets and inhibits… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Purpose This phase III, randomized, placebo-controlled, double-blind study determined whether motesanib improved progression-free… Expand
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2014
2014
Cancer cells often become resistant to chemotherapy through a phenomenon known as multidrug resistance (MDR). Several factors are… Expand
2013
2013
Medullary thyroid carcinoma (MTC), a rare malignancy arising from the parafollicular C cells of the thyroid gland, accounts for… Expand
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Review
2012
Review
2012
  • E. Wolin
  • Gastrointestinal cancer research : GCR
  • 2012
  • Corpus ID: 42865288
BACKGROUND Neuroendocrine tumors (NETs) are neoplasms arising most often in the GI tract, pancreas, or lung. Diagnosis of NETs is… Expand
2009
2009
[1] ten Bokkel Huinink W, Gore M, Carmichael J, Gordon A, Malfetano J, Hudson I, et al. Topotecan versus paclitaxel for the… Expand
Highly Cited
2007
Highly Cited
2007
PURPOSE AMG 706 is an investigational, orally bioavailable inhibitor of vascular endothelial growth factor receptors 1, 2, and 3… Expand
Highly Cited
2006
Highly Cited
2006
The growth of solid tumors is dependent on the continued stimulation of endothelial cell proliferation and migration resulting in… Expand
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Review
2006
Review
2006
The epidermal growth factor receptor (EGFR) and its ligands figure prominently in the biology of gliomas, the most common tumors… Expand
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2006
2006
7119 Introduction: AMG 706 is an investigational, oral, multi-kinase inhibitor with both antiangiogenic and direct antitumor… Expand
2006
2006
3030 Background: AMG 706 is an investigational, oral, small molecule multi-kinase inhibitor with both antiangiogenic and direct… Expand