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AMG 706

Known as: AMG-706, AMG706 
An orally bioavailable multiple-receptor tyrosine kinase inhibitor with potential antineoplastic activity. AMG 706 selectively targets and inhibits… Expand
National Institutes of Health

Papers overview

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2017
2017
Purpose This phase III, randomized, placebo-controlled, double-blind study determined whether motesanib improved progression-free… Expand
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2014
2014
Cancer cells often become resistant to chemotherapy through a phenomenon known as multidrug resistance (MDR). Several factors are… Expand
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2009
2009
[1] ten Bokkel Huinink W, Gore M, Carmichael J, Gordon A, Malfetano J, Hudson I, et al. Topotecan versus paclitaxel for the… Expand
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Highly Cited
2007
Highly Cited
2007
PURPOSE AMG 706 is an investigational, orally bioavailable inhibitor of vascular endothelial growth factor receptors 1, 2, and 3… Expand
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2007
2007
Gastrointestinal stromal tumours (GISTs) are rare mesenchymal neoplasms that arise in the wall of the gastrointestinal tract and… Expand
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Highly Cited
2006
Highly Cited
2006
The growth of solid tumors is dependent on the continued stimulation of endothelial cell proliferation and migration resulting in… Expand
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2006
2006
7119 Introduction: AMG 706 is an investigational, oral, multi-kinase inhibitor with both antiangiogenic and direct antitumor… Expand
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2006
2006
13005 Background: AMG 706 is an investigational, oral, multi-kinase inhibitor with both antiangiogenic and direct antitumor… Expand
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2006
2006
3030 Background: AMG 706 is an investigational, oral, small molecule multi-kinase inhibitor with both antiangiogenic and direct… Expand
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2006
2006
Gastrointestinal stromal tumors (GISTs), the most common mesenchymal tumors in the gastrointestinal tract, metastasize in up to… Expand
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