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Iloprost

Known as: (E)-(3aS,4R,5R,6aS)-Hexahydro-5-hydroxy-4-((E)-(3S,4RS)-3-hydroxy-4-methyl-1-octen-6-ynyl)-delta(sup 2(1H),delta)-pentalenevaleric Acid, Iloprost [Chemical/Ingredient], Pentanoic Acid, 5-(hexahydro-5-hydroxy-4-(3-hydroxy-4-methyl-1-octen-6-ynyl)-2(1H)-pentalenylidene)- 
A prostacyclin analogue with potential chemopreventive activity. Iloprost binds to the prostacyclin receptor in various target cells, thereby causing… 
National Institutes of Health

Related topics

Related topics

20 relations

Narrower (5)

2,6-dichloro-4-aminophenol iloprostVentavisZK-36374eptaloprost
EpoprostenolIloprost 0.01 MG/ML Inhalant SolutionIloprost 0.01 MG/ML Inhalant Solution [Ventavis]In Blood

Broader (3)

Platelet Aggregation InhibitorsProstaglandins, SyntheticVasodilator Agents

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2003
Highly Cited
2003
Exogenous but not endogenous prostanoids regulate cytokine secretion from murine bone marrow dendritic cells: EP2, DP, and IP but not EP1, EP3, and FP prostanoid receptors are involved.
Highly Cited
2002
Highly Cited
2002
Inhaled iloprost controls pulmonary hypertension after cardiopulmonary bypass
PurposeSevere pulmonary hypertension (PH) is a major cause of right ventricular (RV) dysfunction. Various iv vasodilator… 
Review
1999
Review
1999
Hypoxic pulmonary vasoconstriction.
Highly Cited
1994
Highly Cited
1994
Cloning and expression of three isoforms of the human EP3 prostanoid receptor
1994
1994
Cloning and expression of a cDNA for rat prostacyclin receptor.
Highly Cited
1989
Highly Cited
1989
Captopril and ramiprilat protect against free radical injury in isolated working rat hearts.
Highly Cited
1989
Highly Cited
1989
Activation of platelet phospholipase C by fluoride is inhibited by elevation of cyclic AMP.
1988
1988
Evidence for chronic platelet hyperaggregability and in vivo activation in cyclosporin-treated renal allograft recipients.
Review
1987
Review
1987
Eicosanoids and susceptibility to ventricular arrhythmias during myocardial ischaemia and reperfusion.
Highly Cited
1984
Highly Cited
1984
Hemodynamic effects of iloprost, a prostacyclin analog
Iloprost is a chemically stable derivative of carbaprostacyclin. We studied its hemodynamic effects in 10 patients in an… 
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