Iloprost

Known as: (E)-(3aS,4R,5R,6aS)-Hexahydro-5-hydroxy-4-((E)-(3S,4RS)-3-hydroxy-4-methyl-1-octen-6-ynyl)-delta(sup 2(1H),delta)-pentalenevaleric Acid, Iloprost [Chemical/Ingredient], Pentanoic Acid, 5-(hexahydro-5-hydroxy-4-(3-hydroxy-4-methyl-1-octen-6-ynyl)-2(1H)-pentalenylidene)- 
A prostacyclin analogue with potential chemopreventive activity. Iloprost binds to the prostacyclin receptor in various target cells, thereby causing… (More)
National Institutes of Health

Papers overview

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Highly Cited
2006
Highly Cited
2006
Addition of inhaled iloprost to bosentan may have beneficial effects in patients with idiopathic pulmonary arterial hypertension… (More)
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Highly Cited
2003
Highly Cited
2003
OBJECTIVES We sought to investigate the impact of adjunct sildenafil on exercise capacity and hemodynamic parameters in patients… (More)
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Highly Cited
2001
Highly Cited
2001
BACKGROUND The application of iloprost, a stable prostacyclin analogue, by inhalation has been shown to improve hemodynamic… (More)
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Highly Cited
2001
Highly Cited
2001
Patients with scleroderma receiving Iloprost as a treatment for severe Raynaud's phenomenon report a reduction in skin tightness… (More)
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Highly Cited
2000
Highly Cited
2000
BACKGROUND Continuous intravenous infusion of epoprostenol (prostacyclin) is an effective treatment for primary pulmonary… (More)
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Highly Cited
2000
Highly Cited
2000
OBJECTIVE We sought to compare the acute hemodynamic effects of inhaled nitric oxide (NO) and aerosolized iloprost in primary… (More)
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Highly Cited
2000
Highly Cited
2000
Progressive right-heart failure is the ultimate cause of death for most patients with primary pulmonary hypertension. The… (More)
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Highly Cited
1999
Highly Cited
1999
Pulmonary hypertension is a life-threatening complication of lung fibrosis. Vasodilator therapy is difficult owing to systemic… (More)
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Highly Cited
1996
Highly Cited
1996
Primary pulmonary hypertension is a progressive fatal disease of unknown cause, and patients with this condition have a median… (More)
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