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Randomised controlled trial of aspirin and aspirin plus heparin in pregnant women with recurrent miscarriage associated with phospholipid antibodies (or antiphospholipid antibodies)
Abstract Objective: To determine whether treatment with low dose aspirin and heparin leads to a higher rate of live births than that achieved with low dose aspirin alone in women with a history ofExpand
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Guidelines On The Investigation and Management Of The Antiphospholipid Syndrome
In 1991, the Haemostasis and Thrombosis Task Force of the British Society for Haematology published guidelines on testing for the lupus anticoagulant (LA) (Machin et al, 1991). Since then there haveExpand
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Characteristics of ischaemic stroke associated with COVID-19
Coronavirus disease 2019 (COVID19), caused by severe acute respiratory syndrome coronavirus 2 (SARSCoV-2) infection, is associated with coagulopathy causing venous and arterial thrombosis. 2 RecentExpand
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Ten years of hemovigilance reports of transfusion‐related acute lung injury in the United Kingdom and the impact of preferential use of male donor plasma
BACKGROUND AND METHODS: From 1996 through 2006, 195 cases were reported as transfusion‐related acute lung injury (TRALI) to the Serious Hazards of Transfusion scheme and from 1999 onward classifiedExpand
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Remission in acute refractory and relapsing thrombotic thrombocytopenic purpura following rituximab is associated with a reduction in IgG antibodies to ADAMTS‐13
Thrombotic thrombocytopenic purpura (TTP) is a life‐threatening disorder and plasma exchange (PEX) remains the primary treatment modality. Twenty‐five patients with acute refractory/relapsingExpand
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A phase 2 study of the safety and efficacy of rituximab with plasma exchange in acute acquired thrombotic thrombocytopenic purpura.
The safety and efficacy of weekly rituximab 375 mg/m(2) (×4), given within 3 days of acute TTP admission, with standard therapy (PEX and steroids) was evaluated. Clinical outcomes were compared toExpand
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Transfusion guidelines for neonates and older children
This document updates the ‘Guideline for the Administration of Blood Products: Transfusion of Infants and Neonates’, published in 1994. In doing so it acknowledges changes in transfusion practiceExpand
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14th International Congress on Antiphospholipid Antibodies: task force report on antiphospholipid syndrome treatment trends.
Antiphospholipid Syndrome (APS) is characterized by vascular thrombosis and/or pregnancy morbidity occurring in patients with persistent antiphospholipid antibodies (aPL). The primary objective ofExpand
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Serious Hazards of Transfusion (SHOT) haemovigilance and progress is improving transfusion safety
The Serious Hazards of Transfusion (SHOT) UK confidential haemovigilance reporting scheme began in 1996. Over the 16 years of reporting, the evidence gathered has prompted changes in transfusionExpand
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Patient self‐testing is a reliable and acceptable alternative to laboratory INR monitoring
An ageing population and the continuing expansion of clinical indications for coumadin therapy have increased pressure on hospital anticoagulant clinics. One solution is patient self‐testing (PST) ofExpand
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