Skip to search formSkip to main contentSkip to account menu

IkappaB Kinase beta

Known as: IKK 2 Kinase, IKBKB, IKK beta 
National Institutes of Health

Related topics

Related topics

4 relations
IKBKB geneIKBKB wt AlleleInhibitor of Nuclear Factor Kappa-B Kinase Subunit Beta

Broader (1)

IkappaB kinase

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
MicroRNA-16 sensitizes breast cancer cells to paclitaxel through suppression of IKBKB expression
Paclitaxel (Taxol) is an effective chemotherapeutic agent for treating breast cancer patients. However, chemoresistance is a… 
2016
2016
A negative feedback loop between miR‐200b and the nuclear factor‐κB pathway via IKBKB/IKK‐β in breast cancer cells
MicroRNAs (miRNAs) act as important post‐transcriptional regulators of gene expression in diverse signalling pathways. However… 
2007
2007
A critical role for IkappaB kinase beta in metallothionein-1 expression and protection against arsenic toxicity.
Arsenic is a widespread environmental toxic agent that has been shown to cause diverse tissue and cell damage and at the same… 
2005
2005
Cyclin D1 induction through IkappaB kinase beta/nuclear factor-kappaB pathway is responsible for arsenite-induced increased cell cycle G1-S phase transition in human keratinocytes.
Environmental and occupational exposure to arsenite is associated with an increased risk of human cancers, including skin… 
Highly Cited
2005
Highly Cited
2005
Allergen-induced peribronchial fibrosis and mucus production mediated by IkappaB kinase beta-dependent genes in airway epithelium.
In response to inflammation or injury, airway epithelial cells express inducible genes that may contribute to allergen-induced… 
2005
2005
Tumor necrosis factor-alpha triggers mucus production in airway epithelium through an IkappaB kinase beta-dependent mechanism.
Excessive mucus production by airway epithelium is a major characteristic of a number of respiratory diseases, including asthma… 
Highly Cited
2004
Highly Cited
2004
A novel IKKbeta inhibitor stimulates adiponectin levels and ameliorates obesity-linked insulin resistance.
2004
2004
The FcepsilonRIbeta immunoreceptor tyrosine-based activation motif exerts inhibitory control on MAPK and IkappaB kinase phosphorylation and mast cell cytokine production.
The high affinity IgE Fc receptor (FcepsilonRI) beta chain functions as a signal amplifier and has been linked to atopy, asthma… 
2002
2002
Listeriolysin O secreted by Listeria monocytogenes induces NF-kappaB signalling by activating the IkappaB kinase complex.
Listeriolysin O (LLO) is a pore-forming cytolysin secreted by the pathogen Listeria monocytogenes and is required for its… 
2000
2000
Mitogen‐activated kinase kinase kinase 1 regulates T cell receptor‐ and CD28‐mediated signaling events which lead to NF‐κB activation
Optimal activation of Rel / NF‐κB transcription factors in T lymphocytes requires a CD28‐delivered co‐stimulatory signal in… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)