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IKBKB wt Allele
Known as:
IKK2
, FLJ38368
, FLJ33771
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Human IKBKB wild-type allele is located in the vicinity of 8p11.2 and is approximately 61 kb in length. This allele, which encodes inhibitor of…
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National Institutes of Health
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Related topics
Related topics
19 relations
8p11.2
Adipocytokine Signaling Pathway
Apoptosis
B Cell Receptor Signaling Pathway
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Broader (1)
IKBKB gene
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
BRCA 1-Mimetic Compound NSC 35446 . Hcl Inhibits IKKB Expression by Reducing Estrogen Receptor-Occupancy in the IKKB Promoter and Inhibits NF-B Activity in Antiestrogen-Resistant Human Breast Cancer…
Shyam Nathan
,
Yongxian Ma
,
Y. Tomita
,
E. D. Oliveira
,
Milton L. Brown
,
E. Rosen
2017
Corpus ID: 44049762
This dissertation examines the mechanism of action of the BRCA1-mimetic compound NSC35446.HCl and identifies a potential…
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2017
2017
ASSESSING OBESITY AND INSULIN MOLECULAR PATHWAYS INVOLVED IN WEIGHT LOSS INDUCED BY ROUX-EN-Y GASTRIC BYPASS
M. Pinhel
,
C. Ferreira
,
+5 authors
C. Barbosa
2017
Corpus ID: 198243352
Introduction: Given the role genetics plays in weight regulation, the magnitude of weight loss after Roux-en-Y gastric bypass…
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2015
2015
Untersuchungen zur Funktion von IKKb in der durch konstitutiv aktives CARMA1 vermittelten Lymphoproliferation
Louisa Nitsch
2015
Corpus ID: 171713519
Die Arbeit zeigt, dass IKKb bedeutend fur Erkrankung und Tod eines murinen, konstitutiv aktiven CARMA1-Modells ist. Der Fokus in…
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Review
2014
Review
2014
Bacterial safety of lettuce in primary production and fresh-cut processing industry
K. Holvoet
2014
Corpus ID: 111511126
Fresh-cut or ready-to-eat produce including raw produce are becoming more popular due to changes in people’s lifestyle and…
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2014
2014
Curcumin-based IKKβ inhibiting anticancer lead design using novel fragment-based group QSAR modelling
Kunal Patel
,
C. Tyagi
,
Sukriti Goyal
,
J. Dhanjal
,
N. Bharadvaja
,
A. Grover
Medicinal Chemistry Research
2014
Corpus ID: 253645782
NF-κB transcription factor plays a vital role in the protection of transformed cells from apoptosis, thus resulting in the onset…
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2012
2012
The role of IKK2 in TNF-alpha-induced migration and proliferation of human mesenchymal stem cells
E. Pappou
2012
Corpus ID: 83837891
Review
2009
Review
2009
The critical role of atypical protein kinase C in activating hepatic SREBP-1 c and NF k B in obesity Mini
P. Sajan
,
M. Standaert
,
+6 authors
Robert V Farese
2009
Corpus ID: 6004769
Obesity is frequently associated with systemic insulin resistance, glucose intolerance, and hyperlipidemia. Impaired insulin…
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2008
2008
A JNK 1 / AP-1 – Dependent , COX-2 Induction Is Implicated in 12-O-Tetradecanoylphorbol-13-Acetate – Induced Cell Transformation through Regulating Cell Cycle Progression
Dongyun Zhang
,
Jingxia Li
,
Lun Song
,
W. Ouyang
,
Jimin Gao
,
Chuanshu Huang
2008
Corpus ID: 34372529
Cyclooxygenase-2 (COX-2) is reported to be one of the early-response gene products induced by 12-O-tetradecanoylphorbol-13…
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2007
2007
Synthesis and Structure Activity Relationship Studies of Benzothieno [ 3 , 2-b ] furan Derivatives as a Novel Class of IKK b Inhibitors
Hideyuki
,
Sugiyama
,
+13 authors
Yoshinori
2007
Corpus ID: 52102411
kinase complex, which phosphorylates the inhibitor of NFkB (IkB). This complex is composed of three subunits, i.e. the catalytic…
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2005
2005
Indole derivatives and their use as kinase inhibitors, in particular IKK2 inhibitors
I. Baldwin
,
P. Bamborough
,
J. Christopher
,
J. Kerns
,
Timothy Longstaff
,
David D. Miller
2005
Corpus ID: 90912143
A compound of formula (I) ** ** see formula wherein R1 represents H, halogen, or a group -YZ Y represents a bond (ie is absent it…
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