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Ischemia/reperfusion injury.
Abstract Ischemia followed by reperfusion of the rat hind limb resulted in local evidence of injury, as reflected in increased vascular permeability and hemorrhage in skeletal muscle as well asExpand
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Ischemic and non-ischemic acute kidney injury cause hepatic damage.
Recent studies have documented that remote organs are affected by ischemic injury to the kidney. Here we studied whether the liver also suffers damage during induction of renal ischemia-reperfusionExpand
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Upregulation of Phagocyte-Derived Catecholamines Augments the Acute Inflammatory Response
Following our recent report that phagocytic cells (neutrophils, PMNs, and macrophages) are newly discovered sources of catecholamines, we now show that both epinephrine and norepinephrine directlyExpand
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In vivo suppression of NF-kappa B and preservation of I kappa B alpha by interleukin-10 and interleukin-13.
IL-10 and IL-13 have powerful antiinflammatory activities in vitro and in vivo. In the IgG immune complex model of lung injury in rats, exogenously administered IL-10 or IL-13 have recently beenExpand
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Chemokine involvement in hepatic ischemia/reperfusion injury in mice: Roles for macrophage inflammatory protein‐2 and KC
Hepatic injury induced by ischemia and reperfusion is an important clinical problem after liver resection or transplantation. Neutrophils are known to mediate the organ injury, but the preciseExpand
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The Cannabinoid Receptor 2 Is Critical for the Host Response to Sepsis1
Leukocyte function can be modulated through the cannabinoid receptor 2 (CB2R). Using a cecal ligation and puncture (CLP) model of sepsis, we examined the role of the CB2R during the immune responseExpand
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Peroxiredoxin-6 protects against mitochondrial dysfunction and liver injury during ischemia-reperfusion in mice.
Hepatic ischemia-reperfusion (I/R) injury is an important complication of liver surgery and transplantation. Mitochondrial function is central to this injury. To examine alterations in mitochondrialExpand
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Requirement for interleukin‐12 in the pathogenesis of warm hepatic ischemia/reperfusion injury in mice
Hepatic ischemia and reperfusion causes neutrophil‐dependent liver injury. Although the mechanisms of ischemia/reperfusion‐induced liver neutrophil recruitment are somewhat understood, less is knownExpand
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