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Inhibitor of Nuclear Factor Kappa-B Kinase Subunit Beta

Known as: IKK2, NFKBIKB, IKK-Beta 
Inhibitor of nuclear factor kappa-B kinase subunit beta (756 aa, ~87 kDa) is encoded by the human IKBKB gene. This protein is involved in serine… 
National Institutes of Health

Related topics

Related topics

26 relations
Adipocytokine Signaling PathwayApoptosisB Cell Receptor Signaling PathwayCytoplasm

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Correction: Genetic Variants of IκB Kinase β (IKBKB) and Polymerase β (POLB) Were Not Associated with Systemic Lupus Erythematosus Risk in a Chinese Han Population
The first and second author affiliations are switched. The affiliations should appear as shown here: Yuan Li , Ziyan Wu, Shulan… 
2010
2010
Η ανασταλτική κινάση IKK2 είναι σημαντικός ρυθμιστής της παραγωγής της πρωτεΐνης ΜCP-1 από μεσαγγειακά κύτταρα μετά από διέγερση με τον παράγοντα TNF-α in vitro
Σκοπός: Η ανασταλτική κινάση 2 του πυρηνικού παράγοντα-κΒ (inhibitory-κ-Β κινάση 2, Ι-κ-Β kinase-2, IKK2), παίζe… 
2009
2009
Upregulation of RGS 4 expression by IL-1 in colonic smooth muscle is enhanced by ERK 1 / 2 and p 38 MAPK and inhibited by the PI 3 K / Akt / GSK 3 pathway
Hu W, Li F, Mahavadi S, Murthy KS. Upregulation of RGS4 expression by IL-1 in colonic smooth muscle is enhanced by ERK1/2 and p38… 
2008
2008
Inhibition of I K BKinase Subunit 2 in CutaneousT-Cell Lymphoma Down-Regulates Nuclear Factor-K B Constitutive Activation , Induces Cell Death , and Potentiates theApoptotic Response toAntineoplastic…
Purpose: A key molecular feature of cutaneousT-cell lymphomas (CTCL) is the constitutive activation of the nuclear factor-nB (NF… 
2007
2007
Erratum: Targeted ablation of IKK2 improves skeletal muscle strength, maintains mass, and promotes regeneration (Journal of Clinical Investigation (2006) 116 (2945-2954) DOI:10.1172/JCI28721)
2006
2006
The effect of IKK2 inhibition on NF-kappaB activation and macrophage function in atherosclerosis
2004
2004
Targeting NF-κB activation via pharmacological inhibition of IKK2 induced apoptosis of human Acute Myeloid Leukemia cells. Running title : Targeting NF-κB in Acute Myeloid Leukemias
Prepublished online September 28, 2004; Dreano, Nicolas Sirvent and Jean-Francois Peyron Patrick Philip, Christian Dageville… 
2002
2002
Effects of TCDD upon IkappaB and IKK subunits localized in microsomes by proteomics.
Biochemical studies have shown that microsomes represent an important subcellular fraction for determining 2,3,7,8… 
2002
2002
VEGF EXPRESSION IN HUMAN MACROPHAGES IS NF kappa B-DEPENDENT: STUDIES USING ADENOVIRUSES EXPRESSING A KINASE DEFECTIVE FORM OF IKK2 or I kappa B alpha THE NATURAL NF kappa B INHIBITOR
2002
2002
SELECTIVE USAGE OF IKK2 FOR NF-kappa B ACTIVATION AND PRO-INFLAMMATORY GENE EXPRESSION: STUDIES IN HUMAN PRIMARY CELLS AND RHEUMATOID SYNOVIAL MEMBRANE CELL CULTURES