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ITGAL wt Allele

Known as: CD11A, LFA-1, Integrin Subunit Alpha L wt Allele 
Human ITGAL wild-type allele is located in the vicinity of 16p11.2 and is approximately 50 kb in length. This allele, which encodes integrin alpha-L… 
National Institutes of Health

Related topics

Related topics

11 relations
16p11.2CD11a AntigenCTL-mediated Immune Response PathwayCell Adhesion

Broader (1)

ITGAL gene

Papers overview

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2006
2006
TRAIL gene reorganizes the cytoskeleton and decreases the motility of human leukemic Jurkat cells.
TRAIL can selectively induce rapid apoptosis of various types of tumor cells. We induced the expression of TRAIL in Jurkat cells… 
1998
1998
[Effects of the serum obtained from smoke inhalation injury rats on PMN adhesion and transmigration in vitro].
OBJECTIVE This study was conducted to determine the changes in PMN adhesive capacity to endothelial cells and transmigration… 
1996
1996
Obstructive jaundice causes reduced expression of polymorphonuclear leucocyte adhesion molecules and a depressed response to bacterial wall products in vitro.
BACKGROUND--Obstructive jaundice is associated with an increased incidence of infection and endotoxaemia, which may result from… 
1996
1996
Human lymphocyte adhesion to xenogeneic porcine endothelial cells: modulation by human TNF-alpha and involvement of VLA-4 and LFA-1.
1996
1996
Deficient expression of adhesion molecules by human CD5- B lymphocytes both after bone marrow transplantation and during normal ontogeny.
Despite the relatively early reconstitution of blood B-lymphocyte counts observed in patients treated with bone marrow… 
1994
1994
Influence of hyposensitization on soluble interleukin‐2 receptor, eosinophil cationic protein, in vitro lymphocyte proliferation, in vitro lymphocyte adhesion, and lymphocyte membrane markers in…
Soluble interleukin‐2 receptor (sIL‐2R), eosinophil cationic protein (ECP), the lymphoproliferative response to house‐dust mite… 
Highly Cited
1992
Highly Cited
1992
Inhibition of lymphocyte endothelial adhesion and in vivo lymphocyte migration to cutaneous inflammation by TA-3, a new monoclonal antibody to rat LFA-1.
Lymphocyte function-associated Ag-1 (LFA-1) or CD11a/CD18 mediates lymphocyte adhesion to cultured vascular endothelial cells (EC… 
1991
1991
Role of leucocyte integrins in phagocyte responses to granulocyte‐macrophage colony stimulating factor (GM‐CSF): in vitro and in vivo studies on leucocyte adhesion deficiency neutrophils
The role of leucocyte integrins in phagocyte function has been studied by comparing normal neutrophils with those from a patient… 
Highly Cited
1990
Highly Cited
1990
Participation of CD11a‐c/CD18, CD2 and ROD‐binding receptors in endogenous and interleukin‐2‐stimulated NK activity of CDS‐negative large granular lymphocytes
The effect of RGD‐sequence‐containing pentapeptides and monoclonal antibodies (MAbs) against the adhesion molecules CD) la‐c/CDIB… 
Highly Cited
1989
Highly Cited
1989
Two leukocyte receptors (CD11a/CD18 and CD11b/CD18) mediate transient adhesion to endothelium by binding to different ligands.
Upon stimulation with C5a, TNF, or phorbol dibutyrate (PDB), polymorphonuclear leukocytes (PMN) exhibit first an increase then a… 
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