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ITGAL gene

Known as: CD11A, Integrin Subunit Alpha L Gene, INTEGRIN, ALPHA-L 
This gene plays a role in leukocyte intercellular adhesion.
National Institutes of Health

Related topics

Related topics

9 relations
CD11A Expressing Cell CountCD11a AntigenCell AdhesionITGB2 gene

Narrower (2)

ITGAL wt AlleleLymphocyte Function-Associated Antigen-1

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Cyclic stretch induced gene expression of extracellular matrix and adhesion molecules in human periodontal ligament cells.
Highly Cited
2014
Highly Cited
2014
Hypomethylation and overexpression of ITGAL (CD11a) in CD4+ T cells in systemic sclerosis
BackgroundThe pathogenesis and etiology of systemic sclerosis (SSc) are complex and poorly understood. To date, several studies… 
Highly Cited
2013
Highly Cited
2013
Modulation of Enhancer Looping and Differential Gene Targeting by Epstein-Barr Virus Transcription Factors Directs Cellular Reprogramming
Epstein-Barr virus (EBV) epigenetically reprogrammes B-lymphocytes to drive immortalization and facilitate viral persistence… 
Review
2011
Review
2011
Epigenetics in systemic lupus erythematosus: leading the way for specific therapeutic agents.
Systemic lupus erythematosus (SLE) is a chronic autoimmune disorder of an unclearly determined etiology. Past studies, both… 
2010
2010
VEGF₁₆₄ differentially regulates neutrophil and T cell adhesion through ItgaL- and ItgaM-dependent mechanisms.
Leukocyte recruitment to inflamed tissues is the cornerstone of inflammatory responses and the driving force behind the… 
2009
2009
Gene expression signatures in peripheral blood cells from Japanese women exposed to environmental cadmium.
2009
2009
Genetic Deficiency of Itgb2 or ItgaL Prevents Autoimmune Diabetes Through Distinctly Different Mechanisms in NOD/LtJ Mice
OBJECTIVE Insulitis is an important pathological feature of autoimmune diabetes; however, mechanisms governing the recruitment of… 
Review
2008
Review
2008
Epigenetics in human autoimmunity
Epigenetic mechanisms are essential for normal development and function of the immune system. Similarly, a failure to maintain… 
Highly Cited
2002
Highly Cited
2002
Demethylation of ITGAL (CD11a) regulatory sequences in systemic lupus erythematosus.
OBJECTIVE Inhibition of T cell DNA methylation causes autoreactivity in vitro and a lupus-like disease in vivo, suggesting that T… 
Highly Cited
2002
Highly Cited
2002
Age-dependent DNA methylation changes in the ITGAL (CD11a) promoter
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