IRF7 protein, human

Known as: IRF7, Interferon Regulatory Factor 7, IRF-7 
Interferon regulatory factor 7 (503 aa, ~54 kDa) is encoded by the human IRF7 gene. This protein plays a role in the cellular response to viral… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1997-2017
0204019972017

Papers overview

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Highly Cited
2005
Highly Cited
2005
The type-I interferon (IFN-α/β) response is critical to immunity against viruses and can be triggered in many cell types by… (More)
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Highly Cited
2005
Highly Cited
2005
Robust type-I interferon (IFN-α/β) induction in plasmacytoid dendritic cells, through the activation of Toll-like receptor 9… (More)
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Highly Cited
2004
Highly Cited
2004
Toll-like receptors (TLRs) are involved in the recognition of microbial pathogens. A subset of TLRs, TLR7, TLR8 and TLR9, induces… (More)
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Highly Cited
2004
Highly Cited
2004
In humans, the type I interferon (IFN) family consists of 13 IFN-alpha subtypes, IFN-beta and IFN-omicron the newly discovered… (More)
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Highly Cited
2004
Highly Cited
2004
Toll-like receptor (TLR) activation is central to immunity, wherein the activation of the TLR9 subfamily members TLR9 and TLR7… (More)
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Highly Cited
2003
Highly Cited
2003
Rapid induction of type I interferon expression, a central event in establishing the innate antiviral response, requires… (More)
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Highly Cited
2000
Highly Cited
2000
Induction of the interferon (IFN)-alpha/beta gene transcription in virus-infected cells is an event central to innate immunity… (More)
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Highly Cited
1998
Highly Cited
1998
We have identified a virus-activated factor (VAF) that binds to a regulatory element shared by different virus-inducible genes… (More)
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Highly Cited
1998
Highly Cited
1998
Interferon (IFN) genes are among the earliest transcriptional responses to virus infection of mammalian cells. Although the… (More)
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Highly Cited
1998
Highly Cited
1998
The interferon regulatory factor (IRF) family of transcription factors regulate the interferon (IFN) system, among which IRF-3 is… (More)
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