IRF7 gene

Known as: IRF7H, IRF7, IRF7A 
This gene plays a role in the modulation of the innate immune response against DNA and RNA viruses.
National Institutes of Health

Papers overview

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Review
2016
Review
2016
Influenza viruses cause mild to moderate respiratory illness in most people, and only rarely devastating or fatal infections. The… (More)
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2014
2014
Tissue microenvironment influences the function of resident and infiltrating myeloid-derived cells. In the central nervous system… (More)
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Highly Cited
2011
Highly Cited
2011
Recognition of viruses by pattern recognition receptors (PRRs) causes interferon-β (IFN-β) induction, a key event in the anti… (More)
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2011
2011
OBJECTIVE A previous genome-wide association study conducted in a population of European ancestry identified rs4963128, a… (More)
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Highly Cited
2010
Highly Cited
2010
Toll-like receptor 9 (TLR9) senses microbial DNA and triggers type I IFN responses in plasmacytoid dendritic cells (pDCs… (More)
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Highly Cited
2009
Highly Cited
2009
On recognition of influenza virus (Flu) by TLR7, plasmacytoid dendritic cells (pDCs) produce type I IFN in significant amounts… (More)
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Highly Cited
2007
Highly Cited
2007
Upon viral infection, the major defense mounted by the host immune system is activation of the interferon (IFN)-mediated… (More)
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Highly Cited
2005
Highly Cited
2005
Many viruses encode proteins that counteract the development of the interferon (IFN)-mediated antiviral state. Here, we report… (More)
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Highly Cited
2005
Highly Cited
2005
Interferon regulatory factors (IRFs) are critical components of virus-induced immune activation and type I interferon regulation… (More)
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2005
2005
We have reported evidence for a positive regulatory circuit between interferon regulatory factor 7 (IRF7) and the Epstein-Barr… (More)
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