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IRF5 gene

Known as: INTERFERON REGULATORY FACTOR 5, IRF5, Interferon Regulatory Factor 5 Gene 
This gene is involved in the transcriptional regulation of genes encoding interferons and inflammatory cytokines.
National Institutes of Health

Related topics

Related topics

5 relations
Antiviral ResponseHomo sapiensIRF5 protein, humanTranscriptional Activation

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Evaluating the role of nucleic acid antigens in murine models of systemic lupus erythematosus.
Impaired apoptotic cell clearance is thought to contribute to the pathogenesis of systemic autoimmune disease, in particular… 
2014
2014
177 The Alpha-ketoglutarate Receptor GPR99 Regulates Pathological Cardiac Hypertrophy
Introduction GPR99, a member of G-protein coupled receptor family, is expressed in the heart. Previous studies suggested that… 
2012
2012
Methylation profile of the promoter region of IRF5 in primary Sjögren's syndrome.
The transcription factor interferon regulatory factor 5 (IRF5), in the type I interferon pathway is involved in the genetic… 
2011
2011
The CREM gene is involved in genetic predisposition to inflammatory bowel disease in the Tunisian population.
2011
2011
Preferential Association of Interferon Regulatory Factor 5 Gene Variants with Seronegative Rheumatoid Arthritis in 2 Swedish Case-Control Studies
Objective. Two interferon regulatory factor 5 (IRF5) gene variants were examined for association with rheumatoid arthritis (RA… 
2010
2010
Lack of Association Between IRF5 Gene Polymorphisms and Biopsy-proven Giant Cell Arteritis
Objective. Interferon (IFN) regulatory factors (IRF) are transcriptional mediators of IFN-induced signaling pathways and are… 
2010
2010
Clinical Images: Entero-Behçet's disease.
Alarcon-Riquelme ME. Association of STAT4 and BLK, but not BANK1 or IRF5, with primary antiphospholipid syndrome. Arthritis Rheum… 
2009
2009
Association between the rs2004640 functional polymorphism of interferon regulatory factor 5 and systemic lupus erythematosus: a meta-analysis
The aim of this study is to determine whether the functional interferon regulatory factor 5 (IRF5) polymorphism, rs2004640… 
Highly Cited
2007
Highly Cited
2007
Association of a Common Interferon Regulatory Factor 5 (IRF5) Variant with Increased Risk of Systemic Lupus Erythematosus (SLE)
Interferon regulatory factor 5 (IRF5) belongs to a family of transcription factors that control the transactivation of type I… 
2006
2006
Lack of association between IFNGR 1 gene polymorphisms and biopsy-proven giant cell arteritis
1Instituto de Parasitología y Biomedicina López Neyra, Consejo Superior de Investigaciones Cientificas (CSIC), Granada, Spain… 
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