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IRF5 gene

Known as: INTERFERON REGULATORY FACTOR 5, IRF5, Interferon Regulatory Factor 5 Gene 
This gene is involved in the transcriptional regulation of genes encoding interferons and inflammatory cytokines.
National Institutes of Health

Related topics

Related topics

5 relations
Antiviral ResponseHomo sapiensIRF5 protein, humanTranscriptional Activation

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2012
2012
Brief Report: IRF5 systemic lupus erythematosus risk haplotype is associated with asymptomatic serologic autoimmunity and progression to clinical autoimmunity in mothers of children with neonatal…
OBJECTIVE Variation in the interferon regulatory factor 5 (IRF5) gene has been associated with risk of developing systemic lupus… 
2012
2012
Gene–Gene and Gene-Sex Epistatic Interactions of MiR146a, IRF5, IKZF1, ETS1 and IL21 in Systemic Lupus Erythematosus
Several confirmed genetic susceptibility loci involved in the interferon signaling and Th17/B cell response for SLE in Chinese… 
2012
2012
Methylation profile of the promoter region of IRF5 in primary Sjögren's syndrome.
The transcription factor interferon regulatory factor 5 (IRF5), in the type I interferon pathway is involved in the genetic… 
2011
2011
The CREM gene is involved in genetic predisposition to inflammatory bowel disease in the Tunisian population.
2009
2009
Association between the rs2004640 functional polymorphism of interferon regulatory factor 5 and systemic lupus erythematosus: a meta-analysis
The aim of this study is to determine whether the functional interferon regulatory factor 5 (IRF5) polymorphism, rs2004640… 
2008
2008
Putative Role of Functional Interferon Regulatory Factor 5 (IRF5) Polymorphism in Rheumatoid Arthritis in a Korean Population
Objective Recent studies suggest that polymorphisms of interferon regulatory factor 5 (IRF5) are significantly associated with… 
Highly Cited
2007
Highly Cited
2007
Opposed independent effects and epistasis in the complex association of IRF5 to SLE
Genetic variation in the interferon regulatory factor 5 (IRF5) gene affects systemic lupus erythematosus (SLE) susceptibility… 
Highly Cited
2007
Highly Cited
2007
Association of a Common Interferon Regulatory Factor 5 (IRF5) Variant with Increased Risk of Systemic Lupus Erythematosus (SLE)
Interferon regulatory factor 5 (IRF5) belongs to a family of transcription factors that control the transactivation of type I… 
2007
2007
The IRF5 polymorphism in type 1 diabetes
The interferon regulatory factor 5 gene (IRF5) has been shown to play a crucial role in harmful immune responses by induction of… 
2006
2006
IRF5 rs2004640-T allele, the new genetic factor for systemic lupus erythematosus, is not associated with rheumatoid arthritis
Background: Recently, a new genetic factor within the interferon regulatory factor 5 (IRF5) gene was demonstrated for systemic… 
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