IQGAP1 gene

Known as: IQGAP1, IQ MOTIF-CONTAINING GTPase-ACTIVATING PROTEIN 1, IQ motif containing GTPase activating protein 1 
 
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
Invadopodia are actin-based membrane protrusions formed at contact sites between invasive tumor cells and the extracellular… (More)
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Highly Cited
2004
Highly Cited
2004
IQGAP1 binds several proteins including actin, calmodulin, E-cadherin, beta-catenin, Cdc42, Rac1, and CLIP-170. The interaction… (More)
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Highly Cited
2004
Highly Cited
2004
Rho family GTPases, particularly Rac1 and Cdc42, are key regulators of cell polarization and directional migration. Adenomatous… (More)
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Highly Cited
2002
Highly Cited
2002
Linkage of microtubules to special cortical regions is essential for cell polarization. CLIP-170 binds to the growing ends of… (More)
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Highly Cited
1998
Highly Cited
1998
The small guanosine triphosphatases (GTPases) Cdc42 and Rac1 regulate E-cadherin-mediated cell-cell adhesion. IQGAP1, a target of… (More)
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Highly Cited
1998
Highly Cited
1998
During microtubule depolymerization, the central, juxtanuclear Golgi apparatus scatters to multiple peripheral sites. We have… (More)
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Highly Cited
1997
Highly Cited
1997
Activated forms of the GTPases, Rac and Cdc42, are known to stimulate formation of microfilament-rich lamellipodia and filopodia… (More)
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Highly Cited
1996
Highly Cited
1996
Proteins that associate with the GTP-bound forms of the Ras superfamily of proteins are potential effector targets for these… (More)
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Highly Cited
1994
Highly Cited
1994
Two new members (Sar1a and Sar1b) of the SAR1 gene family have been identified in mammalian cells. Using immunoelectron… (More)
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Highly Cited
1987
Highly Cited
1987
Merozoites of the malaria parasite Plasmodium falciparum carry surface proteins processed from a precursor termed p190 or p195… (More)
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