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IQGAP1 gene

Known as: IQGAP1, IQ MOTIF-CONTAINING GTPase-ACTIVATING PROTEIN 1, IQ motif containing GTPase activating protein 1 
National Institutes of Health

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IQGAP3 gene

Papers overview

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Highly Cited
2016
Highly Cited
2016
Reactivation of epigenetically silenced miR-124 reverses the epithelial-to-mesenchymal transition and inhibits invasion in endometrial cancer cells via the direct repression of IQGAP1 expression
Overexpression of IQGAP1 and microRNA (miRNA) dysregulation are frequent in human tumors, but little is known about the role of… 
Highly Cited
2003
Highly Cited
2003
Identification and characterization of the Cdc42-binding site of IQGAP1.
Highly Cited
2001
Highly Cited
2001
Localization of IQGAP1 is inversely correlated with intercellular adhesion mediated by e‐cadherin in gastric cancers
Down‐regulation of E‐cadherin function is characteristic of cancer cells and might involve the small G‐protein Rho family… 
Highly Cited
2001
Highly Cited
2001
IQGAP1, a negative regulator of cell-cell adhesion, is upregulated by gene amplification at 15q26 in gastric cancer cell lines HSC39 and 40A
AbstractOur previous comparative genomic hybridization (CGH) study revealed a novel amplified region at 15q26 in two cell lines… 
Highly Cited
1999
Highly Cited
1999
Localization of the PAK1-, WASP-, and IQGAP1-specifying Regions of Cdc42*
The Rho family small GTPase Cdc42 transmits divergent intracellular signals through multiple effector proteins to elicit cellular… 
1999
1999
Identification of SEC12, SED4, truncated SEC16, and EKS1/HRD3 as multicopy suppressors of ts mutants of Sar1 GTPase.
The yeast SAR1 gene encodes a low-molecular-weight GTPase which is essential for the formation of transport vesicles from the… 
1997
1997
A peptide composed of tandem analogs of two myasthenogenic T cell epitopes interferes with specific autoimmune responses.
Myasthenia gravis (MG) is a T cell-regulated, antibody-mediated autoimmune disease. Two peptides representing sequences of the… 
1996
1996
Peptide analogs to pathogenic epitopes of the human acetylcholine receptor alpha subunit as potential modulators of myasthenia gravis.
Myasthenia gravis is an autoimmune disease in which T cells specific to epitopes of the autoantigen, the human acetylcholine… 
Highly Cited
1991
Highly Cited
1991
sar1, a gene from Schizosaccharomyces pombe encoding a protein that regulates ras1.
Proper ras1 function is required for normal sexual function in the yeast Schizosaccharomyces pombe. We have found a gene in S… 
Highly Cited
1982
Highly Cited
1982
Mechanism of captopril-induced drinking.
Captopril (SQ 14,225), an orally active angiotensin I-converting enzyme (ACE) inhibitor, increased drinking and produced water… 
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