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ING2 gene

Known as: ING1L, ING2, Inhibitor of Growth Family, Member 2 Gene 
This gene plays a role in the modulation of both protein acetylation and apoptosis.
National Institutes of Health

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ApoptosisColon CarcinomaHistone DeacetylationING2 protein, human

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ING2 wt Allele

Papers overview

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Review
2011
Review
2011
Regulation of p53 by ING family members in suppression of tumor initiation and progression
The INhibitor of Growth (ING) family is an evolutionarily conserved set of proteins, implicated in suppression of initiation and… 
Highly Cited
2010
Highly Cited
2010
Deacetylase inhibitors dissociate the histone-targeting ING2 subunit from the Sin3 complex.
2010
2010
HECT ubiquitin ligase Smurf1 targets the tumor suppressor ING2 for ubiquitination and degradation
2010
2010
ING2 controls the G1 to S-phase transition by regulating p21 expression
ING2 (Inhibitor of Growth 2) is a candidate tumor suppressive protein frequently lost in human tumors. Recently, we have reported… 
2008
2008
The role of inositol signaling in the control of apoptosis.
2008
2008
ING2 recruits histone methyltransferase activity with methylation site specificity distinct from histone H3 lysines 4 and 9.
2007
2007
Stabilized phosphatidylinositol-5-phosphate analogues as ligands for the nuclear protein ING2: chemistry, biology, and molecular modeling.
The interaction of PtdIns(5)P with the tumor suppressor protein ING2 has been implicated in the regulation of chromatin… 
2006
2006
Alterations in novel candidate tumor suppressor genes, ING1 and ING2 in human lung cancer.
The ING1 gene is involved in the regulation of the cell cycle, senescence, and apoptosis and is a novel candidate tumor… 
2005
2005
Multiple variants of the ING1 and ING2 tumor suppressors are differentially expressed and thyroid hormone-responsive in Xenopus laevis.
1991
1991
After X-irradiation a transient arrest of L929 cells inG2-phase coincides with a rapid elevation of the level of O6-alkylguanine-DNA alkyltransferase
SummaryFollowing X-irradiation of exponentially growing L929 cells two major phenomena have been observed. First, there was a… 
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